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ClinicalTrials.gov 5 recruiting now full pipeline small index

Post-Polycythemia Vera Myelofibrosis: full-pipeline trial registry

5 of 10 indexed Post-Polycythemia Vera Myelofibrosis trials are currently recruiting.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Post-Polycythemia Vera Myelofibrosis: 10 US clinical trials tracked, 5 recruiting.

Post-Polycythemia Vera Myelofibrosis is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is NS Pharma, running 1 of these trials.

Enrollment posture brief

Registry condition post-polycythemia-vera-myelofibrosis

OPEN 5 | RECR 50% | LATE 4 | EARLY 6 | RANK #1724 | SPON 1

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Acute Leukemia of Ambiguous 80%Post-Polycythemia Vera M (th…50%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Post-Polycythemia Vera Myelofibrosis

Post-Polycythemia Vera Myelofibrosis lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Post-Polycythemia Vera Myelofibrosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Post-Polycythemia Vera Myelofibrosis is recruiting above its size-band peers.

    5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Post-Polycythemia Vera Myelofibrosis trials is spread across many organizations.

    NS Pharma accounts for 1 of 10 trials (10%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Post-Polycythemia Vera Myelofibrosis trials plan to enrol fewer than 100 people.

    Median target enrolment is 84 among the 10 trials that report a genuine target (sentinel values excluded). 6 of those (60%) plan for fewer than 100 participants.

  4. Post-Polycythemia Vera Myelofibrosis research is mostly interventional.

    10 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 34

Open and recent trials

10 total, page 1 of 1

RECRUITING Phase 3 400 participants

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

Merck Sharp & Dohme

NCT06351631

RECRUITING Phase 3 399 participants

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

Swedish Orphan Biovitrum

NCT03165734

RECRUITING Phase 1 76 participants

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

Ajax Therapeutics

NCT06343805

RECRUITING Phase 1 33 participants

Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)

M.D. Anderson Cancer Center

NCT06327100

RECRUITING Phase 1 24 participants

Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Fox Chase Cancer Center

NCT06218628

ACTIVE NOT RECRUITING Phase 3 430 participants

Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)

Novartis Pharmaceuticals

NCT04603495

ACTIVE NOT RECRUITING Phase 3 313 participants

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

Celgene

NCT04717414

ACTIVE NOT RECRUITING Phase 1 84 participants

INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

Incyte Corporation

NCT04455841

COMPLETED Phase 1 77 participants

Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

NS Pharma

NCT01423851

COMPLETED Phase 1 21 participants

MPN-RC 118 AVID200 in Myelofibrosis

John Mascarenhas

NCT03895112

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 3 4

Named interventions

Most-linked intervention names on Post-Polycythemia Vera Myelofibrosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Ruxolitinib Drug
2 trials
AVID200 Drug
1 trials
NS-018 Drug
1 trials
ruxolitinib Drug
1 trials
Tasquinimod Drug
1 trials
ACE-536 Drug
1 trials
pacritinib Drug
1 trials
Bomedemstat Drug
1 trials

US sites by state

Facility locations filed on Post-Polycythemia Vera Myelofibrosis trials. A trial with sites in several states counts in each.

Texas 6 trials
New York 6 trials
Michigan 6 trials
California 6 trials
Florida 5 trials
Missouri 4 trials
Illinois 4 trials
Pennsylvania 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Post-Polycythemia Vera Myelofibrosis page

10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Post-Polycythemia Vera Myelofibrosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • NS Pharma sponsors the most Post-Polycythemia Vera Myelofibrosis trials on record, review their full trial history before evaluating a specific study. See NS Pharma's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post-Polycythemia Vera Myelofibrosis condition card totals 10 registered trials; most-linked intervention Ruxolitinib; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.