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COMPLETED Phase 1

Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF

NCT01423851 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine the safety and tolerability of orally administered NS-018 in patients with Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (post-PV MF), or Post-essential Thrombocythemia Myelofibrosis (post-ET MF)

Interventions

  • DRUG NS-018

Study Locations (9)

Illinois

  • Northwestern University — Chicago
  • University of Chicago — Chicago

Arizona

  • Mayo Clinic Scottsdale Recruiting — Scottsdale

California

  • UC San Diego Moores Cancer Center — San Diego

Florida

  • Mayo Clinic, Jacksonville — Jacksonville

Massachusetts

  • Dana Farber Cancer Institute — Boston

Michigan

  • University of Michigan — Ann Arbor

New York

  • Weill Cornell Medical College — New York

Texas

  • MD Anderson Cancer Center, Department of Leukemia — Houston

Trial Details

FieldValue
Enrollment Target 77 participants
Start Date 2011-06
Est. Completion 2020-04-22
Phase Phase 1

Sponsor

NS Pharma

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01423851

The ClinicalTrials.gov registry entry for NCT01423851 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 77 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NS Pharma, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Primary Myelofibrosis appearing as the primary indexed condition, and to 1 intervention — of which NS-018 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01423851 reports 9 study locations spanning 8 distinct geographic areas — top geographies include Illinois, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01423851 about?

NCT01423851 is a clinical study titled "Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF". The purpose of this study is to determine the safety and tolerability of orally administered NS-018 in patients with Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (post-PV MF), or Post-essential Thrombocythemia Myelofibrosis (post-ET MF)

What is the current status of trial NCT01423851?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 77 participants. The study started on 2011-06. Estimated completion is 2020-04-22.

What conditions does trial NCT01423851 study?

This clinical trial studies the following conditions: Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01423851?

The interventions under investigation include: NS-018 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01423851?

This trial is sponsored by NS Pharma, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01423851 being conducted?

This trial has 9 study locations across Arizona, California, Florida, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial