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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Post-Concussion Syndrome: early-phase trial registry

5 of 15 indexed Post-Concussion Syndrome trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 5 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Post-Concussion Syndrome: 15 US clinical trials tracked, 5 recruiting.

Post-Concussion Syndrome is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Cognitive FX, running 1 of these trials.

Enrollment posture brief

Registry condition post-concussion-syndrome

OPEN 5 | RECR 33% | LATE 0 | EARLY 1 | RANK #1140 | SPON 1

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Advanced Lung Non-Small Cell53.3%Post-Concussion Syndrome (th…33%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Post-Concussion Syndrome

Post-Concussion Syndrome lists 5 open slots (33% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Post-Concussion Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Post-Concussion Syndrome is recruiting below its size-band peers.

    5 of 15 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Post-Concussion Syndrome trials is spread across many organizations.

    Cognitive FX accounts for 1 of 15 trials (6.7%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Most Post-Concussion Syndrome trials plan to enrol fewer than 100 people.

    Median target enrolment is 34 among the 15 trials that report a genuine target (sentinel values excluded). 12 of those (80%) plan for fewer than 100 participants.

  4. Post-Concussion Syndrome research is mostly interventional.

    11 interventional and 4 observational studies make up this index (73.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Open and recent trials

15 total, page 1 of 1

RECRUITING NA 125 participants

Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

Children's Hospital of Orange County

NCT04978571

RECRUITING Phase 2 75 participants

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

University of California, Los Angeles

NCT06073886

RECRUITING NA 55 participants

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

University of Wisconsin, Madison

NCT07044596

RECRUITING 25 participants

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

Northwell Health

NCT04685772

RECRUITING NA 10 participants

Post-concussion Syndrome and Chiropractic

Life University

NCT06151184

ACTIVE NOT RECRUITING NA 200 participants

Mobile Subthreshold Exercise Program for Concussion--R01

Seattle Children's Hospital

NCT04688255

ACTIVE NOT RECRUITING NA 31 participants

Cerebellar TDCS for SRPCS Treatment

University of Iowa

NCT04760899

ACTIVE NOT RECRUITING NA 15 participants

Brain Stimulation for Concussion

The Mind Research Network

NCT05889117

COMPLETED 100 participants

Measure of Cerebrovascular Dysfunction After TBI With fNIRS

Uniformed Services University of the Health Sciences

NCT01789164

COMPLETED 67 participants

Craniosacral Therapy for Concussion Symptoms

Special Therapies

NCT04820192

COMPLETED NA 48 participants

"Interactive Metronome Technology for Blast-Related Traumatic Brain Injury"

The Defense and Veterans Brain Injury Center

NCT01248390

COMPLETED NA 34 participants

Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology

University of Illinois at Urbana-Champaign

NCT03674398

COMPLETED NA 30 participants

Aerobic Training for Management of Post-Concussion Syndrome in Adolescents

Children's Hospital Medical Center, Cincinnati

NCT02035579

COMPLETED NA 15 participants

Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome

University of Missouri-Columbia

NCT04681742

COMPLETED 11 participants

Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome

Cognitive FX

NCT07211919

Phase Distribution

PhaseTrial count
Phase 2 1

Named interventions

Most-linked intervention names on Post-Concussion Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

CO-OP Group Behavioral
1 trials
Interactive metronome Behavioral
1 trials
Stretching Intervention Behavioral
1 trials
Aerobic Training Intervention Behavioral
1 trials
Craniosacral Therapy Other
1 trials
Exercise only Behavioral
1 trials
Exercise+CT Behavioral
1 trials
Intermittent theta-burst treatment (iTBS) using MagPro Transcranial Magnetic Stimulator (manufacturer: Magventure) Device
1 trials

US sites by state

Facility locations filed on Post-Concussion Syndrome trials. A trial with sites in several states counts in each.

Wisconsin 2 trials
California 2 trials
Washington 1 trials
Utah 1 trials
Ohio 1 trials
New York 1 trials
New Mexico 1 trials
Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Post-Concussion Syndrome page

15 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Post-Concussion Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Cognitive FX sponsors the most Post-Concussion Syndrome trials on record, review their full trial history before evaluating a specific study. See Cognitive FX's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post-Concussion Syndrome condition card totals 15 registered trials; most-linked intervention CO-OP Group; top US site state Wisconsin. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.