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ClinicalTrials.gov 5 recruiting now official registry

Post-Concussion Syndrome clinical trials

5 of 15 indexed Post-Concussion Syndrome trials are currently recruiting.

15 US clinical trials · 5 currently recruiting

Post-Concussion Syndrome is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Cognitive FX, running 1 of these trials.

The research picture

Post-Concussion Syndrome has 15 registered US clinical trials, 5 of them open to new participants right now, about 33% of the total.

5
recruiting participants now
33%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
1
top sponsor: Cognitive FX
Phase 21

Active & Recent Trials

15 total, page 1 of 1

RECRUITING NA 125 participants

Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

Children's Hospital of Orange County

NCT04978571

RECRUITING Phase 2 75 participants

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

University of California, Los Angeles

NCT06073886

RECRUITING NA 55 participants

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

University of Wisconsin, Madison

NCT07044596

RECRUITING 25 participants

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

Northwell Health

NCT04685772

RECRUITING NA 10 participants

Post-concussion Syndrome and Chiropractic

Life University

NCT06151184

ACTIVE NOT RECRUITING NA 200 participants

Mobile Subthreshold Exercise Program for Concussion--R01

Seattle Children's Hospital

NCT04688255

ACTIVE NOT RECRUITING NA 31 participants

Cerebellar TDCS for SRPCS Treatment

University of Iowa

NCT04760899

ACTIVE NOT RECRUITING NA 15 participants

Brain Stimulation for Concussion

The Mind Research Network

NCT05889117

COMPLETED 100 participants

Measure of Cerebrovascular Dysfunction After TBI With fNIRS

Uniformed Services University of the Health Sciences

NCT01789164

COMPLETED 67 participants

Craniosacral Therapy for Concussion Symptoms

Special Therapies

NCT04820192

COMPLETED NA 48 participants

"Interactive Metronome Technology for Blast-Related Traumatic Brain Injury"

The Defense and Veterans Brain Injury Center

NCT01248390

COMPLETED NA 34 participants

Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology

University of Illinois at Urbana-Champaign

NCT03674398

COMPLETED NA 30 participants

Aerobic Training for Management of Post-Concussion Syndrome in Adolescents

Children's Hospital Medical Center, Cincinnati

NCT02035579

COMPLETED NA 15 participants

Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome

University of Missouri-Columbia

NCT04681742

COMPLETED 11 participants

Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome

Cognitive FX

NCT07211919

Phase Distribution

PhaseTrial count
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Post-Concussion Syndrome Trial Landscape

15 indexed Post-Concussion Syndrome studies · 5 recruiting (33%).

Phase mix: 0 late (III/IV) vs 1 early (I/II).

Top sponsor: Cognitive FX (1 trial), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Post-Concussion Syndrome?

PlainTrial tracks 15 US clinical trials for Post-Concussion Syndrome, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Post-Concussion Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.