Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Phenylketonurias: early-phase trial registry
3 of 6 indexed Phenylketonurias trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Phenylketonurias: 6 US clinical trials tracked, 3 recruiting.
Phenylketonurias is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Missouri-Columbia, running 2 of these trials.
Enrollment posture brief
Registry condition phenylketonurias
OPEN 3 | RECR 50% | LATE 0 | EARLY 1 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
Phenylketonurias lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Phenylketonurias on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Phenylketonurias is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Phenylketonurias research.
University of Missouri-Columbia accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Most Phenylketonurias trials plan to enrol fewer than 100 people.
Median target enrolment is 30 among the 6 trials that report a genuine target (sentinel values excluded). 6 of those (100%) plan for fewer than 100 participants.
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Phenylketonurias research leans observational.
2 interventional and 4 observational studies make up this index (33.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU)
Emory University
NCT04404530
Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria
University of Missouri-Columbia
NCT06560736
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
NGGT
NCT06332807
Remote Neurocognitive and Psychological Assessment in PKU
University of Missouri-Columbia
NCT04943393
PheCheck Feasibility Study
Lumos Diagnostics
NCT05998109
Bone Mineral Density in Adults With Hyperphenylalaninemia
The University of Texas Health Science Center, Houston
NCT01209819
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Phenylketonurias records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Phenylketonurias trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Phenylketonurias page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Phenylketonurias trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Missouri-Columbia sponsors the most Phenylketonurias trials on record, review their full trial history before evaluating a specific study. See University of Missouri-Columbia's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Phenylketonurias condition card totals 6 registered trials; most-linked intervention Dried Blood Spot Cards; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.