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ClinicalTrials.gov official registry

Pertussis clinical trials

Every US clinical trial registered for Pertussis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

15 US clinical trials ·

The research picture

Pertussis has 15 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
6
top sponsor: Sanofi Pasteur, a Sanofi Company

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

COMPLETED 327,293 participants

Descriptive, Post-marketing, Passive Surveillance Safety Study of ADACEL™ Vaccine

Sanofi Pasteur, a Sanofi Company

NCT00258882

COMPLETED NA 206,703 participants

How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice

Endeavor Health

NCT01979588

COMPLETED Phase 3 3,372 participants

Study of DTap-IPV Compared to DAPTACEL® and IPOL® as the 5th Dose in Children 4 to 6 Years of Age

Sanofi Pasteur, a Sanofi Company

NCT01346293

COMPLETED 1,517 participants

Boostrix® Pregnancy Registry

GlaxoSmithKline

NCT02096276

COMPLETED Phase 4 1,394 participants

Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age

Sanofi Pasteur, a Sanofi Company

NCT01659996

COMPLETED Phase 4 1,302 participants

Study of Adacel® Vaccine Administered to Persons 10 Years of Age

Sanofi

NCT01311557

COMPLETED Phase 4 989 participants

Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™

Sanofi Pasteur, a Sanofi Company

NCT00802867

COMPLETED Phase 4 647 participants

Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®

Sanofi

NCT00319553

COMPLETED Phase 4 545 participants

Descriptive, Open-label, Multicenter Study of the Safety of Redosing With ADACEL® Vaccine

Sanofi Pasteur, a Sanofi Company

NCT00347958

COMPLETED Phase 4 423 participants

Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents

Sanofi Pasteur, a Sanofi Company

NCT01629589

COMPLETED Phase 2 399 participants

Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their Infants

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03589768

COMPLETED NA 300 participants

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00013871

COMPLETED Phase 1 80 participants

Pertussis Vaccine in Healthy Pregnant Women

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00707148

COMPLETED Phase 2 50 participants

Safety and Immunogenicity of Intranasal BPZE1 Vaccination in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03541499

COMPLETED Phase 2 5 participants

Pentavalent DTaP-Hep B-IPV

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00133445

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pertussis Trial Landscape

ClinicalTrials.gov lists 15 US studies indexed under Pertussis, and 0 of those are currently open to recruitment — roughly 0% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pertussis shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pertussis is led by Sanofi Pasteur, a Sanofi Company with 6 indexed trials, alongside 4 other organizations in the top contributor list. The list on this page surfaces up to 15 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pertussis?

PlainTrial tracks 15 US clinical trials for Pertussis, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pertussis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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