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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Paraganglioma: early-phase trial registry

7 of 12 indexed Paraganglioma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 7 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Paraganglioma: 12 US clinical trials tracked, 7 recruiting.

Paraganglioma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

Enrollment posture brief

Registry condition paraganglioma

OPEN 7 | RECR 58% | LATE 1 | EARLY 9 | RANK #1429 | SPON 3

Nearest open-share peer: Anterior Cruciate Ligament Reconstruction (58% recruiting · 12 trials)

Paraganglioma (this)58%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Paraganglioma

Paraganglioma lists 7 open slots (58% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Paraganglioma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Paraganglioma is recruiting above its size-band peers.

    7 of 12 indexed trials (58.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Paraganglioma research.

    National Cancer Institute (NCI) accounts for 3 of 12 trials (25%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Paraganglioma enrolment sits around 30 participants.

    Median target enrolment is 30 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Paraganglioma research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 41

Open and recent trials

12 total, page 1 of 1

RECRUITING 2,000 participants

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

The University of Texas Health Science Center at San Antonio

NCT03160274

RECRUITING NA 1,000 participants

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

University of Pennsylvania

NCT06377033

RECRUITING Phase 1 260 participants

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Neuroendocrine Tumors

Perspective Therapeutics

NCT05636618

RECRUITING Phase 4 200 participants

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

Weill Medical College of Cornell University

NCT04081701

RECRUITING Phase 2 130 participants

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

National Cancer Institute (NCI)

NCT03206060

RECRUITING Early Phase 1 30 participants

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

Heather Wachtel

NCT05636540

RECRUITING Phase 1 18 participants

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Anusha Kalbasi

NCT04119024

ACTIVE NOT RECRUITING Phase 2 14 participants

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

National Cancer Institute (NCI)

NCT05142241

ACTIVE NOT RECRUITING Phase 2 11 participants

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

Advanced Accelerator Applications

NCT04711135

ACTIVE NOT RECRUITING Phase 2 10 participants

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

Antonio Fojo

NCT03946527

ACTIVE NOT RECRUITING Phase 2 6 participants

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

Columbia University

NCT03839498

COMPLETED Phase 2 14 participants

Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma

National Cancer Institute (NCI)

NCT01967576

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 4 1

Named interventions

Most-linked intervention names on Paraganglioma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
2 trials
Biospecimen Collection Procedure
2 trials
Axitinib (AG-013736) Drug
1 trials
Lutetium [177Lu] oxodotreotide/dotatate Drug
1 trials
[18F]FluorThanatrace ([18F]FTT) Drug
1 trials
Behavioral nudge Behavioral
1 trials
Genetic screening Genetic
1 trials
Ga68-DOTATATE-PET/MRI Diagnostic test
1 trials

US sites by state

Facility locations filed on Paraganglioma trials. A trial with sites in several states counts in each.

Maryland 4 trials
Pennsylvania 3 trials
Ohio 3 trials
New York 3 trials
Kentucky 2 trials
Washington 1 trials
Virginia 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Paraganglioma page

12 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Paraganglioma condition card totals 12 registered trials; most-linked intervention Computed Tomography; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.