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ClinicalTrials.gov 1 recruiting now later-stage tilt small index

Neurotoxicity: later-stage trial registry

1 of 11 indexed Neurotoxicity trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 1 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Neurotoxicity: 11 US clinical trials tracked, 1 recruiting.

Neurotoxicity is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Alliance for Clinical Trials in Oncology, running 3 of these trials.

Enrollment posture brief

Registry condition neurotoxicity

OPEN 1 | RECR 9% | LATE 6 | EARLY 1 | RANK #1577 | SPON 3

Nearest open-share peer: Advanced Cancers (9% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%Neurotoxicity (this)9%
Open-enrollment share among volume-matched conditions near Neurotoxicity

Neurotoxicity lists 1 open slots (9% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neurotoxicity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neurotoxicity is recruiting below its size-band peers.

    1 of 11 indexed trials (9.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Neurotoxicity research.

    Alliance for Clinical Trials in Oncology accounts for 3 of 11 trials (27.3%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Neurotoxicity enrolment sits around 104 participants.

    Median target enrolment is 104 among the 11 trials that report a genuine target (sentinel values excluded). 4 of those (36.4%) plan for fewer than 100 participants.

  4. Neurotoxicity research is mostly interventional.

    8 interventional and 3 observational studies make up this index (72.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 36

Open and recent trials

11 total, page 1 of 1

RECRUITING 100 participants

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

M.D. Anderson Cancer Center

NCT06144151

ACTIVE NOT RECRUITING Phase 3 540 participants

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Eastern Cooperative Oncology Group

NCT00978458

ACTIVE NOT RECRUITING Phase 3 450 participants

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics

Murdoch Childrens Research Institute

NCT03089905

COMPLETED Phase 3 250 participants

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

University of South Florida

NCT00369564

COMPLETED Phase 3 231 participants

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Alliance for Clinical Trials in Oncology

NCT00489411

COMPLETED Phase 3 226 participants

EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer

Alliance for Clinical Trials in Oncology

NCT00046891

COMPLETED Phase 3 104 participants

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery

Alliance for Clinical Trials in Oncology

NCT00316914

COMPLETED 82 participants

Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery

Radiation Therapy Oncology Group

NCT01417507

COMPLETED 81 participants

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

University of California, San Francisco

NCT00755313

COMPLETED Phase 2 80 participants

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

University of California, San Francisco

NCT00003072

COMPLETED NA 39 participants

Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer

Virginia Commonwealth University

NCT01196442

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 6

Named interventions

Most-linked intervention names on Neurotoxicity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

placebo Other
3 trials
questionnaire administration Other
2 trials
carboplatin Drug
2 trials
glutamic acid Drug
1 trials
electrical stimulation pain therapy Other
1 trials
Ginkgo Biloba Drug
1 trials
aromatase inhibition therapy Drug
1 trials
duloxetine hydrochloride Drug
1 trials

US sites by state

Facility locations filed on Neurotoxicity trials. A trial with sites in several states counts in each.

California 5 trials
Georgia 3 trials
Florida 3 trials
Arizona 3 trials
Texas 2 trials
Ohio 2 trials
Minnesota 2 trials
Illinois 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neurotoxicity page

11 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neurotoxicity condition card totals 11 registered trials; most-linked intervention placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.