Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Neuromyelitis Optica: early-phase trial registry
2 of 8 indexed Neuromyelitis Optica trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 2 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Neuromyelitis Optica: 8 US clinical trials tracked, 2 recruiting.
Neuromyelitis Optica is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Texas Southwestern Medical Center, running 2 of these trials.
Enrollment posture brief
Registry condition neuromyelitis-optica
OPEN 2 | RECR 25% | LATE 1 | EARLY 3 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Pain (25% recruiting · 20 trials)
Neuromyelitis Optica lists 2 open slots (25% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Neuromyelitis Optica on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Neuromyelitis Optica is recruiting below its size-band peers.
2 of 8 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Neuromyelitis Optica research.
University of Texas Southwestern Medical Center accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Most Neuromyelitis Optica trials plan to enrol fewer than 100 people.
Median target enrolment is 46 among the 8 trials that report a genuine target (sentinel values excluded). 5 of those (62.5%) plan for fewer than 100 participants.
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Neuromyelitis Optica splits between interventional and observational designs.
5 interventional and 3 observational studies make up this index (62.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD
Ad scientiam
NCT05566769
Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder
University of Texas Southwestern Medical Center
NCT06398158
Biobank For MS And Other Demyelinating Diseases
Accelerated Cure Project for Multiple Sclerosis
NCT00445367
The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders
University of Texas Southwestern Medical Center
NCT01623076
High Frequency Impulse Therapy for Neuropathic Pain in NMOSD
Massachusetts General Hospital
NCT04614454
Safety and Tolerability of Rituximab in Neuromyelitis Optica
University of California, San Francisco
NCT00501748
An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica
Mayo Clinic
NCT00904826
A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)
State University of New York at Buffalo
NCT00304291
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Neuromyelitis Optica records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Neuromyelitis Optica trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Neuromyelitis Optica page
8 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Neuromyelitis Optica trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Texas Southwestern Medical Center sponsors the most Neuromyelitis Optica trials on record, review their full trial history before evaluating a specific study. See University of Texas Southwestern Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neuromyelitis Optica condition card totals 8 registered trials; most-linked intervention High Frequency Impulse Therapy - Sham; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.