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ClinicalTrials.gov 11 recruiting now early-phase tilt small index

Myelodysplastic/Myeloproliferative Neoplasm: early-phase trial registry

11 of 16 indexed Myelodysplastic/Myeloproliferative Neoplasm trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 11 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Myelodysplastic/Myeloproliferative Neoplasm: 16 US clinical trials tracked, 11 recruiting.

Myelodysplastic/Myeloproliferative Neoplasm is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition myelodysplasticmyeloproliferative-neoplasm

OPEN 11 | RECR 69% | LATE 0 | EARLY 14 | RANK #1060 | SPON 3

Nearest open-share peer: Deep Brain Stimulation (69% recruiting · 16 trials)

Myelodysplastic/Myelopro (th…69%Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Myelodysplastic/Myeloproliferative Neoplasm

Myelodysplastic/Myeloproliferative Neoplasm lists 11 open slots (69% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Myelodysplastic/Myeloproliferative Neoplasm on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Myelodysplastic/Myeloproliferative Neoplasm is recruiting above its size-band peers.

    11 of 16 indexed trials (68.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Myelodysplastic/Myeloproliferative Neoplasm research.

    M.D. Anderson Cancer Center accounts for 3 of 16 trials (18.8%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Myelodysplastic/Myeloproliferative Neoplasm trials plan to enrol fewer than 100 people.

    Median target enrolment is 62 among the 16 trials that report a genuine target (sentinel values excluded). 10 of those (62.5%) plan for fewer than 100 participants.

  4. Myelodysplastic/Myeloproliferative Neoplasm research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 26

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 1 260 participants

A Study of BGB-11417 in Participants With Myeloid Malignancies

BeiGene

NCT04771130

RECRUITING NA 207 participants

A Telehealth Advance Care Planning Intervention

University of Rochester

NCT05875805

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 2 62 participants

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

National Cancer Institute (NCI)

NCT06661915

RECRUITING Phase 1 58 participants

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

M.D. Anderson Cancer Center

NCT03630991

RECRUITING Phase 1 52 participants

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

Uma Borate

NCT06523556

RECRUITING Phase 2 50 participants

Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes

Fred Hutchinson Cancer Center

NCT07228624

RECRUITING Phase 1 30 participants

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Fred Hutchinson Cancer Center

NCT06034470

RECRUITING Phase 2 25 participants

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

University of Washington

NCT04282187

RECRUITING Early Phase 1 24 participants

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Omar Aljitawi

NCT03964506

RECRUITING Phase 1 23 participants

Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS

University of Virginia

NCT07270978

ACTIVE NOT RECRUITING Phase 2 204 participants

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

M.D. Anderson Cancer Center

NCT02861417

ACTIVE NOT RECRUITING Phase 2 132 participants

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

NCT05600894

ACTIVE NOT RECRUITING 100 participants

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Massachusetts General Hospital

NCT04902833

ACTIVE NOT RECRUITING Phase 1 64 participants

Phase I/II Study of Tagraxofusp in Combination With Decitabine for Patients With Myelomonocytic/Myeloproliferative Neoplasm and High Risk Myelodysplastic Syndromes

M.D. Anderson Cancer Center

NCT05038592

ACTIVE NOT RECRUITING Phase 2 25 participants

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

National Cancer Institute (NCI)

NCT03289910

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 6

Named interventions

Most-linked intervention names on Myelodysplastic/Myeloproliferative Neoplasm records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
4 trials
Bone Marrow Biopsy Procedure
3 trials
Bone Marrow Aspiration Procedure
3 trials
Allogeneic Hematopoietic Stem Cell Transplantation Procedure
2 trials
Decitabine and Cedazuridine Drug
2 trials
Ruxolitinib Drug
2 trials
Decitabine Drug
2 trials
Azacitidine Drug
2 trials

US sites by state

Facility locations filed on Myelodysplastic/Myeloproliferative Neoplasm trials. A trial with sites in several states counts in each.

Texas 5 trials
New York 4 trials
California 4 trials
Washington 3 trials
Massachusetts 3 trials
Illinois 3 trials
Florida 3 trials
Ohio 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Myelodysplastic/Myeloproliferative Neoplasm page

16 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 11 Myelodysplastic/Myeloproliferative Neoplasm trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • M.D. Anderson Cancer Center sponsors the most Myelodysplastic/Myeloproliferative Neoplasm trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Myelodysplastic/Myeloproliferative Neoplasm condition card totals 16 registered trials; most-linked intervention Biospecimen Collection; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.