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ClinicalTrials.gov official registry

Mycobacterium Avium-Intracellulare Infection clinical trials

All 9 indexed Mycobacterium Avium-Intracellulare Infection trials have closed enrollment.

9 US clinical trials ·

Mycobacterium Avium-Intracellulare Infection is the subject of 9 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 6 of these trials.

The research picture

Mycobacterium Avium-Intracellulare Infection has 9 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
6
top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase 12Phase 31

Active & Recent Trials

9 total, page 1 of 1

COMPLETED Phase 3 1,100 participants

The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001030

COMPLETED NA 750 participants

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

Pharmacia

NCT00002032

COMPLETED 326 participants

Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000933

COMPLETED NA 91 participants

The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001023

COMPLETED 50 participants

A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00000907

COMPLETED Phase 1 15 participants

Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex Infection

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001763

COMPLETED Phase 1 2 participants

Adjuvant Cytokine Therapy to Treat Pulmonary Mycobacterium Avium Complex Infection

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00111397

COMPLETED NA

A Study of Azithromycin in the Prevention of Mycobacterium Avium Complex Disease (MAC) in HIV-Infected Patients

Pfizer

NCT00002309

COMPLETED NA

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study

Pharmacia

NCT00002080

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mycobacterium Avium-Intracellulare Infection Trial Landscape

9 indexed Mycobacterium Avium-Intracellulare Infection studies · 0 recruiting (0%).

Phase mix: 1 late (III/IV) vs 2 early (I/II).

Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (6 trials), 2 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mycobacterium Avium-Intracellulare Infection?

PlainTrial tracks 9 US clinical trials for Mycobacterium Avium-Intracellulare Infection, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mycobacterium Avium-Intracellulare Infection?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.