Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
MPS IVA: early-phase trial registry
3 of 6 indexed MPS IVA trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
MPS IVA: 6 US clinical trials tracked, 3 recruiting.
MPS IVA is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 2 of these trials.
Enrollment posture brief
Registry condition mps-iva
OPEN 3 | RECR 50% | LATE 0 | EARLY 2 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
MPS IVA lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for MPS IVA on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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MPS IVA is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates MPS IVA research.
University of California, San Francisco accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Most MPS IVA trials plan to enrol fewer than 100 people.
Median target enrolment is 17 among the 6 trials that report a genuine target (sentinel values excluded). 5 of those (83.3%) plan for fewer than 100 participants.
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MPS IVA research leans observational.
2 interventional and 4 observational studies make up this index (33.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Cardiac Structure and Function in MPS
Children's Hospital of Orange County
NCT07361536
Non-invasive Functional Assessment and Pathogenesis of Morquio A
Nemours Children's Clinic
NCT05284006
PEARL (PrEnAtal Enzyme Replacement Therapy for Lysosomal Storage Disorders)
University of California, San Francisco
NCT04532047
Safety and Efficacy of Voxzogo for Growth Deficits in MPS IVA and VI
University of California, San Francisco
NCT05845749
Screening an Orthopedic Population for Mildly-affected Individuals With Morquio Syndrome A and Maroteaux-Lamy Syndrome
Greenwood Genetic Center
NCT01961518
Gait Analysis in MPS IVA
Oregon Health and Science University
NCT01920828
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on MPS IVA records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on MPS IVA trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this MPS IVA page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 MPS IVA trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of California, San Francisco sponsors the most MPS IVA trials on record, review their full trial history before evaluating a specific study. See University of California, San Francisco's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This MPS IVA condition card totals 6 registered trials; most-linked intervention Vosoritide Injection [Voxzogo]; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.