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NCT07143370 · ClinicalTrials.gov registry record · NA
Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners
A NA study of Microbial Colonization and Orthodontic Aligner, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07143370: Completed NA study of Microbial Colonization and Orthodontic Aligner, sponsored by University of Michigan.
NCT07143370 is a NA study of Microbial Colonization and Orthodontic Aligner that has completed, run by University of Michigan. The registered enrollment target is 30 participants, below the 12,653-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07143370, a NA study of Microbial Colonization and Orthodontic Aligner, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances. The 3D printed aligner material and conventional aligner materials are being used for investigational purposes and have been approved for their use in fabricating clear aligners for orthodontic tooth movement, but not for the purposes of our study, which is for the fabrication of clear passive aligners to assess microbial colonization.
Primary Outcome
Assessed using a swab to the tooth surface (three times, once for each aligner)
Conditions Studied
Interventions
- DEVICE Thermoformed clear aligner
- DEVICE 3D printed clear aligner TC-85
- DEVICE 3D printed clear aligner TA-28
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-09-02 |
| Est. Completion | 2025-10-17 |
| Phase | NA |
What the finished NCT07143370 record still lists
NCT07143370 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 12,653-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Microbial Colonization appearing as the primary indexed condition, and to 3 interventions - of which Thermoformed clear aligner is the first listed.
NCT07143370 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT07143370 about?
NCT07143370 is a clinical study titled "Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners". This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances. The 3D printed aligner material and conventional aligner materials are being used for investigationa...
What is the current status of trial NCT07143370?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2025-09-02. Estimated completion is 2025-10-17.
What conditions does trial NCT07143370 study?
This clinical trial studies the following conditions: Microbial Colonization, Orthodontic Aligner.
What interventions are being tested in trial NCT07143370?
The interventions under investigation include: Thermoformed clear aligner (DEVICE), 3D printed clear aligner TC-85 (DEVICE), 3D printed clear aligner TA-28 (DEVICE).
Who is sponsoring clinical trial NCT07143370?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07143370 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Microbial Colonization
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07143370's enrollment target sits among peer trials
30 16th of 20 higher than 4 of 20 other Microbial Colonization trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Microbial Colonization trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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