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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Metastatic Malignant Neoplasm in the Liver: early-phase trial registry

7 of 14 indexed Metastatic Malignant Neoplasm in the Liver trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 7 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Metastatic Malignant Neoplasm in the Liver: 14 US clinical trials tracked, 7 recruiting.

Metastatic Malignant Neoplasm in the Liver is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 7 of these trials.

Enrollment posture brief

Registry condition metastatic-malignant-neoplasm-in-the-liver

OPEN 7 | RECR 50% | LATE 2 | EARLY 9 | RANK #1230 | SPON 7

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Metastatic Malignant Neo (th…50%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Metastatic Malignant Neoplasm in the Liver

Metastatic Malignant Neoplasm in the Liver lists 7 open slots (50% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Malignant Neoplasm in the Liver on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Malignant Neoplasm in the Liver is recruiting above its size-band peers.

    7 of 14 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Malignant Neoplasm in the Liver research.

    M.D. Anderson Cancer Center accounts for 7 of 14 trials (50%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Malignant Neoplasm in the Liver trials plan to enrol fewer than 100 people.

    Median target enrolment is 46 among the 14 trials that report a genuine target (sentinel values excluded). 10 of those (71.4%) plan for fewer than 100 participants.

  4. Metastatic Malignant Neoplasm in the Liver research is mostly interventional.

    13 interventional and 1 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 24Phase 31Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 3 408 participants

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

ECOG-ACRIN Cancer Research Group

NCT05863195

RECRUITING Phase 2 141 participants

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

SWOG Cancer Research Network

NCT05040360

RECRUITING Phase 2 140 participants

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

M.D. Anderson Cancer Center

NCT04982653

RECRUITING NA 70 participants

An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response

M.D. Anderson Cancer Center

NCT04796818

RECRUITING Phase 1 40 participants

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

M.D. Anderson Cancer Center

NCT05039632

RECRUITING Phase 1 36 participants

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

University of Southern California

NCT05791448

RECRUITING Phase 4 6 participants

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Vanderbilt-Ingram Cancer Center

NCT06016855

ACTIVE NOT RECRUITING NA 100 participants

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

M.D. Anderson Cancer Center

NCT02156739

ACTIVE NOT RECRUITING Phase 1 38 participants

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

M.D. Anderson Cancer Center

NCT03203525

ACTIVE NOT RECRUITING Phase 1 36 participants

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

M.D. Anderson Cancer Center

NCT02626312

ACTIVE NOT RECRUITING Phase 2 32 participants

Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

Nicholas Fidelman, MD

NCT03457948

ACTIVE NOT RECRUITING Phase 2 28 participants

Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver Metastases

Thomas Jefferson University

NCT04728633

COMPLETED 75 participants

4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis

M.D. Anderson Cancer Center

NCT00862680

COMPLETED Phase 1 46 participants

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

National Cancer Institute (NCI)

NCT02070549

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 4
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Metastatic Malignant Neoplasm in the Liver records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Magnetic Resonance Imaging Procedure
3 trials
Computed Tomography Procedure
3 trials
Bevacizumab Biological
2 trials
Radiation Therapy Radiation
2 trials
Fluorouracil Drug
2 trials
4D PET Scan Procedure
1 trials
4-Dimensional Computed Tomography Procedure
1 trials
Gadoxetate Disodium Drug
1 trials

US sites by state

Facility locations filed on Metastatic Malignant Neoplasm in the Liver trials. A trial with sites in several states counts in each.

Texas 8 trials
California 4 trials
Missouri 2 trials
Michigan 2 trials
Illinois 2 trials
Florida 2 trials
Tennessee 1 trials
Pennsylvania 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Malignant Neoplasm in the Liver page

14 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Metastatic Malignant Neoplasm in the Liver trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • M.D. Anderson Cancer Center sponsors the most Metastatic Malignant Neoplasm in the Liver trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Malignant Neoplasm in the Liver condition card totals 14 registered trials; most-linked intervention Magnetic Resonance Imaging; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.