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ClinicalTrials.gov 6 recruiting now official registry

Metastatic Castration-resistant Prostate Carcinoma clinical trials

6 of 9 indexed Metastatic Castration-resistant Prostate Carcinoma trials are currently recruiting.

9 US clinical trials · 6 currently recruiting

Metastatic Castration-resistant Prostate Carcinoma is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 3 of these trials.

The research picture

Metastatic Castration-resistant Prostate Carcinoma has 9 registered US clinical trials, 6 of them open to new participants right now, about 67% of the total.

6
recruiting participants now
67%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: University of Washington
Phase 13Phase 24Phase 41

Active & Recent Trials

9 total, page 1 of 1

RECRUITING Phase 1 90 participants

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

National Cancer Institute (NCI)

NCT04071236

RECRUITING 60 participants

SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy

University of Michigan Rogel Cancer Center

NCT07096999

RECRUITING Phase 2 51 participants

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

University of Washington

NCT06526299

RECRUITING Phase 1 40 participants

Novel ACK1 Inhibitor (R)-9b in Patients With Prostate Cancer

TechnoGenesys

NCT06705686

RECRUITING Phase 4 30 participants

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

Brigham and Women's Hospital

NCT06099093

RECRUITING Phase 1 30 participants

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Vadim S Koshkin

NCT05113537

ACTIVE NOT RECRUITING Phase 2 141 participants

An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer

University of Washington

NCT04777071

ACTIVE NOT RECRUITING Phase 2 20 participants

Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer

National Cancer Institute (NCI)

NCT05828082

ACTIVE NOT RECRUITING Phase 2 8 participants

Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study

University of Washington

NCT05960578

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastatic Castration-resistant Prostate Carcinoma Trial Landscape

9 indexed Metastatic Castration-resistant Prostate Carcinoma studies · 6 recruiting (67%).

Phase mix: 1 late (III/IV) vs 7 early (I/II).

Top sponsor: University of Washington (3 trials), 5 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastatic Castration-resistant Prostate Carcinoma?

PlainTrial tracks 9 US clinical trials for Metastatic Castration-resistant Prostate Carcinoma, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastatic Castration-resistant Prostate Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.