Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov official registry

Metabolic Syndrome X clinical trials

All 11 indexed Metabolic Syndrome X trials have closed enrollment.

11 US clinical trials ·

Metabolic Syndrome X is the subject of 11 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 5 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Foundation Research, Florida, running 1 of these trials.

The research picture

Metabolic Syndrome X has 11 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
1
top sponsor: Foundation Research, Florida
Phase 22Phase 45

Active & Recent Trials

11 total, page 1 of 1

COMPLETED Phase 2 261 participants

Effects of Resistance and Aerobic Exercise on Cardiovascular Health

Duke University

NCT00275145

COMPLETED NA 114 participants

Collaborative Care for Heart Failure Patients With the Metabolic Syndrome

Baylor College of Medicine

NCT00293852

COMPLETED Phase 4 77 participants

Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes

Veterans Medical Research Foundation

NCT00338949

COMPLETED Phase 4 70 participants

Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome

Florida Atlantic University

NCT00272311

COMPLETED Phase 4 46 participants

Oral Contraceptives in the Metabolic Syndrome

Virginia Commonwealth University

NCT00205504

COMPLETED Phase 2 36 participants

Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells

Emory University

NCT00166036

COMPLETED Phase 4 30 participants

Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia

Foundation Research, Florida

NCT00304993

COMPLETED NA 30 participants

Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers

Tufts University

NCT00175084

COMPLETED NA 26 participants

Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults

Columbia University

NCT02347007

COMPLETED Phase 4 21 participants

Diurnal Variation of Plasminogen Activator Inhibitor-1

Vanderbilt University Medical Center

NCT00515021

COMPLETED NA 16 participants

Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption

Ohio State University

NCT02918422

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metabolic Syndrome X Trial Landscape

11 indexed Metabolic Syndrome X studies · 0 recruiting (0%).

Phase mix: 5 late (III/IV) vs 2 early (I/II).

Top sponsor: Foundation Research, Florida (1 trial), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metabolic Syndrome X?

PlainTrial tracks 11 US clinical trials for Metabolic Syndrome X, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metabolic Syndrome X?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.