Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Locally Advanced Head and Neck Squamous Cell Carcinoma: full-pipeline trial registry
3 of 6 indexed Locally Advanced Head and Neck Squamous Cell Carcinoma trials are currently recruiting.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Locally Advanced Head and Neck Squamous Cell Carcinoma: 6 US clinical trials tracked, 3 recruiting.
Locally Advanced Head and Neck Squamous Cell Carcinoma is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Johnson & Johnson Enterprise Innovation, running 1 of these trials.
Enrollment posture brief
Registry condition locally-advanced-head-and-neck-squamous-cell-carcinoma
OPEN 3 | RECR 50% | LATE 2 | EARLY 3 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
Locally Advanced Head and Neck Squamous Cell Carcinoma lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Locally Advanced Head and Neck Squamous Cell Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Locally Advanced Head and Neck Squamous Cell Carcinoma is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Locally Advanced Head and Neck Squamous Cell Carcinoma research.
Johnson & Johnson Enterprise Innovation accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Locally Advanced Head and Neck Squamous Cell Carcinoma trials plan to enrol fewer than 100 people.
Median target enrolment is 46 among the 6 trials that report a genuine target (sentinel values excluded). 4 of those (66.7%) plan for fewer than 100 participants.
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Locally Advanced Head and Neck Squamous Cell Carcinoma research is mostly interventional.
6 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
AstraZeneca
NCT06129864
JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC
Johnson & Johnson Enterprise Innovation
NCT04892173
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
National Cancer Institute (NCI)
NCT05172245
Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer
Emory University
NCT05245682
Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition
Wake Forest University Health Sciences
NCT04454489
Group-Mediated Cognitive Behavioral Resistance Exercise Intervention in Head and Neck Cancer Patients Undergoing Chemoradiation Treatment
Ohio State University Comprehensive Cancer Center
NCT04733495
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Locally Advanced Head and Neck Squamous Cell Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Locally Advanced Head and Neck Squamous Cell Carcinoma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Locally Advanced Head and Neck Squamous Cell Carcinoma page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Locally Advanced Head and Neck Squamous Cell Carcinoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Johnson & Johnson Enterprise Innovation sponsors the most Locally Advanced Head and Neck Squamous Cell Carcinoma trials on record, review their full trial history before evaluating a specific study. See Johnson & Johnson Enterprise Innovation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Locally Advanced Head and Neck Squamous Cell Carcinoma condition card totals 6 registered trials; most-linked intervention Radiation Therapy; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.