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ClinicalTrials.gov 5 recruiting now early-phase tilt

Kidney Failure, Chronic: early-phase trial registry

5 of 25 indexed Kidney Failure, Chronic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 5 currently recruiting · #652 of 28,707 conditions by registered trial count

Kidney Failure, Chronic: 25 US clinical trials tracked, 5 recruiting.

Kidney Failure, Chronic is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is NxStage Medical, running 2 of these trials.

Enrollment posture brief

Registry condition kidney-failure-chronic

OPEN 5 | RECR 20% | LATE 3 | EARLY 11 | RANK #652 | SPON 2

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (20% recruiting · 10 trials)

Alpha-1 Antitrypsin Deficien48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%Kidney Failure, Chronic (thi…20%
Open-enrollment share among volume-matched conditions near Kidney Failure, Chronic

Kidney Failure, Chronic lists 5 open slots (20% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Kidney Failure, Chronic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Kidney Failure, Chronic is recruiting below its size-band peers.

    5 of 25 indexed trials (20%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Kidney Failure, Chronic trials is spread across many organizations.

    NxStage Medical accounts for 2 of 25 trials (8%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Most Kidney Failure, Chronic trials plan to enrol fewer than 100 people.

    Median target enrolment is 58 among the 24 trials that report a genuine target (sentinel values excluded). 16 of those (66.7%) plan for fewer than 100 participants.

  4. Kidney Failure, Chronic research is mostly interventional.

    21 interventional and 4 observational studies make up this index (84% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 24Phase 31Phase 42

Open and recent trials

25 total, page 1 of 1

RECRUITING 2,000 participants

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

The Rogosin Institute

NCT01802034

RECRUITING 500 participants

International (Pediatric) Peritoneal Biobank

Heidelberg University

NCT01893710

RECRUITING Phase 3 150 participants

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Alessandro Doria

NCT06217302

RECRUITING Phase 1 28 participants

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Eli Lilly and Company

NCT07426380

RECRUITING Phase 1 24 participants

Empagliflozin in ESKD - A Feasibility Study

University of Mississippi Medical Center

NCT05687058

ACTIVE NOT RECRUITING 300 participants

Kidney Function in Sickle Cell Anemia

Kenneth Ataga MD

NCT03277547

ACTIVE NOT RECRUITING Phase 2 90 participants

DePTH: De-emphasize PTH

University of Washington

NCT06288451

ACTIVE NOT RECRUITING Phase 1 20 participants

Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Stanley Jordan, MD

NCT03380962

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 550 participants

Multidisciplinary Inpatient Palliative Care Intervention

Kaiser Permanente

NCT00325611

COMPLETED Phase 2 506 participants

Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)

Merck Sharp & Dohme

NCT05027074

COMPLETED 501 participants

FREEDOM: Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements Study

NxStage Medical

NCT00288613

COMPLETED Phase 2 74 participants

Exercise Intolerance in Renal Failure

Emory University

NCT01356966

COMPLETED NA 58 participants

Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™

NxStage Medical

NCT00667511

COMPLETED NA 58 participants

Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function

Palo Alto Veterans Institute for Research

NCT03874117

COMPLETED NA 58 participants

Dietary Maneuvers to Reduce Production of Colon-Derived Uremic Solutes

Stanford University

NCT01186276

COMPLETED Phase 1 40 participants

A Study to Evaluate JNJ-64565111 Pharmacokinetics and Safety in Adult Participants With Varying Degrees of Renal Function

Janssen Research & Development

NCT03546205

COMPLETED Phase 1 38 participants

Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)

Merck Sharp & Dohme

NCT03873038

COMPLETED NA 36 participants

Exercise in Peritoneal Dialysis Patients (PDEX)

Satellite Healthcare

NCT03980795

COMPLETED Phase 1 31 participants

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

Shire

NCT00875017

COMPLETED Phase 1 24 participants

A Study of Obinutuzumab to Evaluate Safety and Tolerability in Hypersensitized Adult Participants With End Stage Renal Disease Awaiting Transplantation

Hoffmann-La Roche

NCT02586051

COMPLETED Phase 2 19 participants

A Phase II Study to Evaluate the Efficacy of IdeS to Desensitize Transplant Patients With a Positive Crossmatch Test

Hansa Biopharma AB

NCT02790437

COMPLETED Phase 4 17 participants

A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood

Oregon Health and Science University

NCT00212758

COMPLETED Phase 4 5 participants

Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation

Weill Medical College of Cornell University

NCT00629122

COMPLETED NA

Resistance Training and Diet in Patients With Chronic Renal Failure

US Department of Veterans Affairs

NCT00018317

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 4
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Kidney Failure, Chronic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
MK-2060 Drug
2 trials
combination of diet control and exercise Behavioral
1 trials
resistance training Behavioral
1 trials
low protein diet Behavioral
1 trials
Folate Dietary supplement
1 trials
Tetrahydrobiopterin Drug
1 trials
Corn starch Dietary supplement
1 trials

US sites by state

Facility locations filed on Kidney Failure, Chronic trials. A trial with sites in several states counts in each.

California 12 trials
New York 5 trials
Washington 4 trials
Florida 4 trials
Texas 3 trials
Tennessee 3 trials
Ohio 3 trials
Missouri 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Kidney Failure, Chronic page

25 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Kidney Failure, Chronic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • NxStage Medical sponsors the most Kidney Failure, Chronic trials on record, review their full trial history before evaluating a specific study. See NxStage Medical's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Kidney Failure, Chronic condition card totals 25 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.