Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 5 recruiting now official registry

Kidney Failure, Chronic clinical trials

Every US clinical trial registered for Kidney Failure, Chronic — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

25 US clinical trials · 5 currently recruiting

The research picture

Kidney Failure, Chronic has 25 registered US clinical trials, 5 of them open to new participants right now — about 20% of the total.

5
recruiting participants now
20%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: NxStage Medical

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,000 participants

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

The Rogosin Institute

NCT01802034

RECRUITING 500 participants

International (Pediatric) Peritoneal Biobank

Heidelberg University

NCT01893710

RECRUITING Phase 3 150 participants

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Alessandro Doria

NCT06217302

RECRUITING Phase 1 28 participants

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Eli Lilly and Company

NCT07426380

RECRUITING Phase 1 24 participants

Empagliflozin in ESKD - A Feasibility Study

University of Mississippi Medical Center

NCT05687058

ACTIVE NOT RECRUITING 300 participants

Kidney Function in Sickle Cell Anemia

Kenneth Ataga MD

NCT03277547

ACTIVE NOT RECRUITING Phase 2 90 participants

DePTH: De-emphasize PTH

University of Washington

NCT06288451

ACTIVE NOT RECRUITING Phase 1 20 participants

Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant

Stanley Jordan, MD

NCT03380962

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED NA 550 participants

Multidisciplinary Inpatient Palliative Care Intervention

Kaiser Permanente

NCT00325611

COMPLETED Phase 2 506 participants

Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)

Merck Sharp & Dohme

NCT05027074

COMPLETED 501 participants

FREEDOM: Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements Study

NxStage Medical

NCT00288613

COMPLETED Phase 2 74 participants

Exercise Intolerance in Renal Failure

Emory University

NCT01356966

COMPLETED NA 58 participants

Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™

NxStage Medical

NCT00667511

COMPLETED NA 58 participants

Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function

Palo Alto Veterans Institute for Research

NCT03874117

COMPLETED NA 58 participants

Dietary Maneuvers to Reduce Production of Colon-Derived Uremic Solutes

Stanford University

NCT01186276

COMPLETED Phase 1 40 participants

A Study to Evaluate JNJ-64565111 Pharmacokinetics and Safety in Adult Participants With Varying Degrees of Renal Function

Janssen Research & Development

NCT03546205

COMPLETED Phase 1 38 participants

Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)

Merck Sharp & Dohme

NCT03873038

COMPLETED NA 36 participants

Exercise in Peritoneal Dialysis Patients (PDEX)

Satellite Healthcare

NCT03980795

COMPLETED Phase 1 31 participants

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

Shire

NCT00875017

COMPLETED Phase 1 24 participants

A Study of Obinutuzumab to Evaluate Safety and Tolerability in Hypersensitized Adult Participants With End Stage Renal Disease Awaiting Transplantation

Hoffmann-La Roche

NCT02586051

COMPLETED Phase 2 19 participants

A Phase II Study to Evaluate the Efficacy of IdeS to Desensitize Transplant Patients With a Positive Crossmatch Test

Hansa Biopharma AB

NCT02790437

COMPLETED Phase 4 17 participants

A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood

Oregon Health and Science University

NCT00212758

COMPLETED Phase 4 5 participants

Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation

Weill Medical College of Cornell University

NCT00629122

COMPLETED NA

Resistance Training and Diet in Patients With Chronic Renal Failure

US Department of Veterans Affairs

NCT00018317

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 4
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Kidney Failure, Chronic Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Kidney Failure, Chronic, and 5 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Kidney Failure, Chronic shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Kidney Failure, Chronic is led by NxStage Medical with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Kidney Failure, Chronic?

PlainTrial tracks 25 US clinical trials for Kidney Failure, Chronic, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Kidney Failure, Chronic?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →