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Kidney Failure, Chronic clinical trials
Every US clinical trial registered for Kidney Failure, Chronic — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
25 US clinical trials · 5 currently recruiting
The research picture
Kidney Failure, Chronic has 25 registered US clinical trials, 5 of them open to new participants right now — about 20% of the total.
- 5
- recruiting participants now
- 20%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: NxStage Medical
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
The Rogosin Institute
NCT01802034
International (Pediatric) Peritoneal Biobank
Heidelberg University
NCT01893710
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Alessandro Doria
NCT06217302
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Eli Lilly and Company
NCT07426380
Empagliflozin in ESKD - A Feasibility Study
University of Mississippi Medical Center
NCT05687058
Kidney Function in Sickle Cell Anemia
Kenneth Ataga MD
NCT03277547
DePTH: De-emphasize PTH
University of Washington
NCT06288451
Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant
Stanley Jordan, MD
NCT03380962
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
University of Washington
NCT04281784
Multidisciplinary Inpatient Palliative Care Intervention
Kaiser Permanente
NCT00325611
Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)
Merck Sharp & Dohme
NCT05027074
FREEDOM: Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements Study
NxStage Medical
NCT00288613
Exercise Intolerance in Renal Failure
Emory University
NCT01356966
Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™
NxStage Medical
NCT00667511
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
Palo Alto Veterans Institute for Research
NCT03874117
Dietary Maneuvers to Reduce Production of Colon-Derived Uremic Solutes
Stanford University
NCT01186276
A Study to Evaluate JNJ-64565111 Pharmacokinetics and Safety in Adult Participants With Varying Degrees of Renal Function
Janssen Research & Development
NCT03546205
Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)
Merck Sharp & Dohme
NCT03873038
Exercise in Peritoneal Dialysis Patients (PDEX)
Satellite Healthcare
NCT03980795
Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers
Shire
NCT00875017
A Study of Obinutuzumab to Evaluate Safety and Tolerability in Hypersensitized Adult Participants With End Stage Renal Disease Awaiting Transplantation
Hoffmann-La Roche
NCT02586051
A Phase II Study to Evaluate the Efficacy of IdeS to Desensitize Transplant Patients With a Positive Crossmatch Test
Hansa Biopharma AB
NCT02790437
A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood
Oregon Health and Science University
NCT00212758
Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation
Weill Medical College of Cornell University
NCT00629122
Resistance Training and Diet in Patients With Chronic Renal Failure
US Department of Veterans Affairs
NCT00018317
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 4 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Kidney Failure, Chronic Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Kidney Failure, Chronic, and 5 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Kidney Failure, Chronic shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Kidney Failure, Chronic is led by NxStage Medical with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Kidney Failure, Chronic?
PlainTrial tracks 25 US clinical trials for Kidney Failure, Chronic, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Kidney Failure, Chronic?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.