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NCT00875017 · ClinicalTrials.gov registry record · Phase 1

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

A Phase 1 study of Kidney Failure, Chronic, sponsored by Shire.

Completed
Registry status
Phase 1
Development phase
31
Enrollment target
1
Study location

NCT00875017: Completed Phase 1 study of Kidney Failure, Chronic, sponsored by Shire.

NCT00875017 is a Phase 1 study of Kidney Failure, Chronic that has completed, run by Shire. The registered enrollment target is 31 participants, below the 331-participant average among 23 other Kidney Failure, Chronic trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00875017, a Phase 1 study of Kidney Failure, Chronic, has completed, sponsored by Shire.

COMPLETED
Registry status
Phase 1
Development phase
31 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to compare the absorption of dietary phosphorus following a single dose with lanthanum carbonate (1000mg) and a single dose of sevelamer carbonate (2400mg).

Primary Outcome

Net phosphorous absorption (Lanthanum carbonate period) = phosphorous ingested in meal minus (Rectal effluent phosphorous after Lanthanum carbonate + meal minus Rectal effluent phosphorous after fasting). Net phosphorous absorption (Sevelamer Carbonate period) = Phosphorous ingested in meal minus (Rectal effluent phosphorous after Sevelamer carbonate + meal minus Rectal effluent phosphorous after fasting). Net phosphorous absorption (Meal only period) = Phosphorous ingested in meal minus (Rectal

Conditions Studied

Interventions

  • DRUG Sevelamer
  • DRUG Lanthanum Carbonate

Study Locations (1)

California

  • West Coast Clinical Trials - Cypress

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2009-04-20
Est. Completion 2009-06-16
Phase Phase 1
Shire

245 total trials

What the finished NCT00875017 record still lists

NCT00875017 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 331-participant average among 23 other Kidney Failure, Chronic trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Kidney Failure, Chronic appearing as the primary indexed condition, and to 2 interventions - of which Sevelamer is the first listed.

NCT00875017 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT00875017 about?

NCT00875017 is a clinical study titled "Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers". The purpose of this study is to compare the absorption of dietary phosphorus following a single dose with lanthanum carbonate (1000mg) and a single dose of sevelamer carbonate (2400mg).

What is the current status of trial NCT00875017?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2009-04-20. Estimated completion is 2009-06-16.

What conditions does trial NCT00875017 study?

This clinical trial studies the following conditions: Kidney Failure, Chronic.

What interventions are being tested in trial NCT00875017?

The interventions under investigation include: Sevelamer (DRUG), Lanthanum Carbonate (DRUG).

Who is sponsoring clinical trial NCT00875017?

This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00875017 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Kidney Failure, Chronic

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00875017's enrollment target sits among peer trials

31 17th of 23 higher than 7 of 23 other Kidney Failure, Chronic trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Kidney Failure, Chronic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00875017, the US trial registry maintained by the National Library of Medicine. NCT00875017 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.