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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

High Risk Pregnancy: early-phase trial registry

7 of 11 indexed High Risk Pregnancy trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 7 currently recruiting · #1,577 of 28,707 conditions by registered trial count

High Risk Pregnancy: 11 US clinical trials tracked, 7 recruiting.

High Risk Pregnancy is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Medical College of Wisconsin, running 2 of these trials.

Enrollment posture brief

Registry condition high-risk-pregnancy

OPEN 7 | RECR 64% | LATE 0 | EARLY 1 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Melanoma (64% recruiting · 22 trials)

Acute Pancreatitis81.8%High Risk Pregnancy (this)64%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near High Risk Pregnancy

High Risk Pregnancy lists 7 open slots (64% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for High Risk Pregnancy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. High Risk Pregnancy is recruiting above its size-band peers.

    7 of 11 indexed trials (63.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates High Risk Pregnancy research.

    Medical College of Wisconsin accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical High Risk Pregnancy enrolment sits around 148 participants.

    Median target enrolment is 148 among the 11 trials that report a genuine target (sentinel values excluded). 3 of those (27.3%) plan for fewer than 100 participants.

  4. High Risk Pregnancy splits between interventional and observational designs.

    6 interventional and 5 observational studies make up this index (54.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Open and recent trials

11 total, page 1 of 1

RECRUITING NA 1,000 participants

Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage

Baymatob Operations Pty

NCT06655207

RECRUITING 1,000 participants

UCLA Perinatal Biospecimen Repository

Yalda Afshar, MD, PhD

NCT05035160

RECRUITING NA 118 participants

Leg Heating in Pregnant Women With Obesity

University of Texas Southwestern Medical Center

NCT06932250

RECRUITING NA 100 participants

Preventing Obstetric Complications With Dietary Intervention

Medical College of Wisconsin

NCT06320054

RECRUITING Phase 2 55 participants

IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

David Ware Branch

NCT03152058

RECRUITING 50 participants

Remote Fetal Monitoring in High Risk Pregnancies

Beth Israel Deaconess Medical Center

NCT06822439

RECRUITING 30 participants

Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Medical College of Wisconsin

NCT03775954

COMPLETED 379 participants

Placenta Imaging Project

Oregon Health and Science University

NCT02749851

COMPLETED 250 participants

The Center for Peripartum Optimization

Johns Hopkins University

NCT03522909

COMPLETED NA 150 participants

Misoprostol With Mechanical Dilation Versus Oxytocin With Mechanical Dilation for High-risk Pregnancy Inductions

Thomas Jefferson University

NCT04492072

COMPLETED NA 148 participants

The Impact of Arts-Based Interventions on Patient Hospital Experience

University of Alabama at Birmingham

NCT04024670

Phase Distribution

PhaseTrial count
Phase 2 1

Named interventions

Most-linked intervention names on High Risk Pregnancy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Seen in clinic Other
1 trials
MRI - Iugr Device
1 trials
Arts Intervention Other
1 trials
Oli is a non-invasive, wearable device, designed to provide clinicians with an early indication if the participant is at a higher risk of developing abnormal postpartum uterine bleeding Device
1 trials
Maternal Health Management Program Behavioral
1 trials
Leg heating Other
1 trials
Certolizumab Pegol Drug
1 trials
Fetal ECG monitoring Device
1 trials

US sites by state

Facility locations filed on High Risk Pregnancy trials. A trial with sites in several states counts in each.

Wisconsin 2 trials
Utah 2 trials
Pennsylvania 2 trials
New York 2 trials
Texas 1 trials
Oregon 1 trials
Ohio 1 trials
Maryland 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this High Risk Pregnancy page

11 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This High Risk Pregnancy condition card totals 11 registered trials; most-linked intervention Seen in clinic; top US site state Wisconsin. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.