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NCT00000273 · ClinicalTrials.gov registry record · Phase 2

A Laboratory Model for Heroin Abuse Medications - 8

A Phase 2 study of Substance-Related Disorders and Opioid-Related Disorders, sponsored by New York State Psychiatric Institute.

Completed
Registry status
Phase 2
Development phase
8
Enrollment target
2
Study locations

NCT00000273: Completed Phase 2 study of Substance-Related Disorders and Opioid-Related Disorders, sponsored by New York State Psychiatric Institute.

NCT00000273 is a Phase 2 study of Substance-Related Disorders and Opioid-Related Disorders that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 8 participants, below the 1,521-participant average among 58 other Substance-Related Disorders trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000273, a Phase 2 study of Substance-Related Disorders and Opioid-Related Disorders, has completed, sponsored by New York State Psychiatric Institute.

COMPLETED
Registry status
Phase 2
Development phase
8 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."

Primary Outcome

All of the participants received all of the drugs tested; drugs and doses were administered in non-systematic order. Participants were instructed to choose between the dose that they had received during the sample session or another reward..

Interventions

  • DRUG opiates

Study Locations (2)

New York

  • Columbia University - New York
  • New York State Psychiatric Institute - New York

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 1995-08
Est. Completion 2005-11
Phase Phase 2

What the finished NCT00000273 record still lists

NCT00000273 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,521-participant average among 58 other Substance-Related Disorders trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Substance-Related Disorders appearing as the primary indexed condition, and to 1 intervention - of which opiates is the first listed.

NCT00000273 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00000273 about?

NCT00000273 is a clinical study titled "A Laboratory Model for Heroin Abuse Medications - 8". The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."

What is the current status of trial NCT00000273?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 1995-08. Estimated completion is 2005-11.

What conditions does trial NCT00000273 study?

This clinical trial studies the following conditions: Substance-Related Disorders, Opioid-Related Disorders, Heroin Dependence.

What interventions are being tested in trial NCT00000273?

The interventions under investigation include: opiates (DRUG).

Who is sponsoring clinical trial NCT00000273?

This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00000273 being conducted?

This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Substance-Related Disorders

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00000273's enrollment target sits among peer trials

8 59th of 58 the lowest of 58 other Substance-Related Disorders trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Substance-Related Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000273, the US trial registry maintained by the National Library of Medicine. NCT00000273 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.