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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Genetic Predisposition to Disease: early-phase trial registry

9 of 12 indexed Genetic Predisposition to Disease trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 9 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Genetic Predisposition to Disease: 12 US clinical trials tracked, 9 recruiting.

Genetic Predisposition to Disease is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 2 of these trials.

Enrollment posture brief

Registry condition genetic-predisposition-to-disease

OPEN 9 | RECR 75% | LATE 0 | EARLY 2 | RANK #1429 | SPON 2

Nearest open-share peer: Activity, Motor (75% recruiting · 8 trials)

Genetic Predisposition t (th…75%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Genetic Predisposition to Disease

Genetic Predisposition to Disease lists 9 open slots (75% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Genetic Predisposition to Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Genetic Predisposition to Disease is recruiting above its size-band peers.

    9 of 12 indexed trials (75%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Genetic Predisposition to Disease research.

    Boston Children's Hospital accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Genetic Predisposition to Disease enrolment sits around 400 participants.

    Median target enrolment is 400 among the 12 trials that report a genuine target (sentinel values excluded). 3 of those (25%) plan for fewer than 100 participants.

  4. Genetic Predisposition to Disease research leans observational.

    4 interventional and 8 observational studies make up this index (33.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21

Open and recent trials

12 total, page 1 of 1

RECRUITING 2,000,000 participants

Helix Research Network

Helix

NCT06057181

RECRUITING 4,000 participants

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Brigham and Women's Hospital

NCT01258231

RECRUITING 1,250 participants

Blood Markers of Early Pancreas Cancer

University of Nebraska

NCT03568630

RECRUITING 750 participants

VIGOR: Virtual Genome Center for Infant Health

Boston Children's Hospital

NCT05205356

RECRUITING 400 participants

Prostate Cancer Genetic Risk Evaluation and Screening Study

Massachusetts General Hospital

NCT05129605

RECRUITING Phase 2 200 participants

Microbiome and Association With Implant Infections

University of California, San Francisco

NCT05020574

RECRUITING 150 participants

Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders

Boston Children's Hospital

NCT03967743

RECRUITING 50 participants

Healthy Volunteers Study

Abramson Cancer Center at Penn Medicine

NCT06962059

RECRUITING NA 40 participants

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Dana-Farber Cancer Institute

NCT05759143

ACTIVE NOT RECRUITING Phase 1 205 participants

This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults

University of Missouri-Columbia

NCT05386914

COMPLETED NA 650 participants

NYCKidSeq: Incorporating Genomics Into Clinical Care of Diverse NYC Children

Icahn School of Medicine at Mount Sinai

NCT03738098

COMPLETED 75 participants

4R for Guideline Indicated BRCA Testing of Breast Center Patients

Northwestern University

NCT01320540

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Named interventions

Most-linked intervention names on Genetic Predisposition to Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

GUÍA Behavioral
1 trials
Prostate cancer screening Diagnostic test
1 trials
Self-Administered Sample Collection Other
1 trials
Nest Platform Behavioral
1 trials
Exome sequencing Genetic
1 trials
Cephalexin Drug
1 trials
Standard of Care Behavioral
1 trials
Sirolimus Drug
1 trials

US sites by state

Facility locations filed on Genetic Predisposition to Disease trials. A trial with sites in several states counts in each.

Massachusetts 5 trials
Texas 3 trials
Pennsylvania 2 trials
New York 2 trials
Nebraska 2 trials
South Dakota 1 trials
South Carolina 1 trials
Ohio 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Genetic Predisposition to Disease page

12 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 9 Genetic Predisposition to Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Boston Children's Hospital sponsors the most Genetic Predisposition to Disease trials on record, review their full trial history before evaluating a specific study. See Boston Children's Hospital's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Genetic Predisposition to Disease condition card totals 12 registered trials; most-linked intervention GUÍA; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.