Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Fluid Overload
Open-data reference.
9 US clinical trials · 5 currently recruiting
Active & Recent Trials
Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning
Lenox Hill Hospital
NCT06418022
Ultrafiltration Versus IV Diuretics in Worsening Heart Failure
Nuwellis
NCT05318105
Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.
University of Michigan
NCT05505500
Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)
Indiana University
NCT07178470
The Effect of Fluids on Aortic VTI During C-section
Baylor College of Medicine
NCT04330742
Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Study.
Medtronic - MITG
NCT04608149
Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04095143
Comparison of Non-Invasive Methods of Assessing Fluid Responsiveness in ED and ICU Patients
Olive View-UCLA Education & Research Institute
NCT02679625
Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure
Sarfez Pharmaceuticals
NCT06995144
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Fluid Overload Trial Landscape
ClinicalTrials.gov lists 9 US studies indexed under Fluid Overload, and 5 of those are currently open to recruitment — roughly 56% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Fluid Overload shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Fluid Overload is led by Olive View-UCLA Education & Research Institute with 1 indexed trial, alongside 8 other organizations in the top contributor list. The list on this page surfaces up to 9 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Fluid Overload?
PlainTrial tracks 9 US clinical trials for Fluid Overload, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Fluid Overload?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.