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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Esophageal Achalasia: early-phase trial registry

2 of 3 indexed Esophageal Achalasia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #5,209 of 28,707 conditions by registered trial count.

3 US clinical trials · 2 currently recruiting · #5,209 of 28,707 conditions by registered trial count

Esophageal Achalasia: 3 US clinical trials tracked, 2 recruiting.

Esophageal Achalasia is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is L. Michael Brunt, running 1 of these trials.

Enrollment posture brief

Registry condition esophageal-achalasia

OPEN 2 | RECR 67% | LATE 0 | EARLY 1 | RANK #5209 | SPON 1

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

Ablation80%ACL Reconstruction80%Esophageal Achalasia (this)67%Abuse, Drug60%Acceptability60%
Open-enrollment share among volume-matched conditions near Esophageal Achalasia

Esophageal Achalasia lists 2 open slots (67% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Esophageal Achalasia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Esophageal Achalasia is recruiting above its size-band peers.

    2 of 3 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 21

Phase Distribution

PhaseTrial count
Phase 2 1

Top Sponsors

Named interventions

Most-linked intervention names on Esophageal Achalasia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Toupet fundoplication Procedure
1 trials
Dor fundoplication Procedure
1 trials
Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies Procedure
1 trials
Biopsy of esophageal/stomach tissue, lymph nodes, tumor Procedure
1 trials
Blood specimen for non-DNA and DNA parts Procedure
1 trials
Survey of client health, personal habits, family history Procedure
1 trials
Pyloromyotomy Procedure
1 trials
Botulinum Toxin A (Botox ) Biological
1 trials

US sites by state

Facility locations filed on Esophageal Achalasia trials. A trial with sites in several states counts in each.

Pennsylvania 1 trials
Ohio 1 trials
Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Esophageal Achalasia page

3 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Esophageal Achalasia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • L. Michael Brunt sponsors the most Esophageal Achalasia trials on record, review their full trial history before evaluating a specific study. See L. Michael Brunt's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Esophageal Achalasia condition card totals 3 registered trials; most-linked intervention Toupet fundoplication; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.