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Esophageal Cancer Risk Registry
NCT00260585 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to identify markers in the blood and tissue that could indicate risk factors for the development and progression of esophagus cancer. This research aims to collect medical history, blood, and tissue samples from patients who present with an esophageal disorder. Identifying genetic and behavioral risk factors involved in the development of esophageal cancer might allow for early detection and prevention. Survival and an opportunity for a cure with esophageal cancer will depend greatly on the stage of diagnosis. Tumors can develop changes in their genetic (hereditary) make-up, and these changes can sometimes be seen in normal tissues before the development of cancer. These genetic (hereditary) changes can serve as tumor markers and can be detected using methods that study changes in genetic material like DNA and RNA. The analysis of proteins can provide additional information. By identifying changes in these molecules that are different or altered in cancer, the investigators can use methods and tests for the detection of these changes.
Conditions Studied
Interventions
- PROCEDURE Survey of client health, personal habits, family history
- PROCEDURE Blood specimen for non-DNA and DNA parts
- PROCEDURE Biopsy of esophageal/stomach tissue, lymph nodes, tumor
- PROCEDURE Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies
Study Locations (1)
Pennsylvania
- Department of Cardiothoracic Surgery — Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,000 participants |
| Start Date | 1999-06 |
| Est. Completion | 2050-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00260585
The ClinicalTrials.gov registry entry for NCT00260585 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 7,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,082 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 4 interventions — of which Survey of client health, personal habits, family history is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00260585 reports 1 study location spanning 1 distinct geographic area — top geographies include Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00260585 about?
NCT00260585 is a clinical study titled "Esophageal Cancer Risk Registry". The purpose of this study is to identify markers in the blood and tissue that could indicate risk factors for the development and progression of esophagus cancer. This research aims to collect medical history, blood, and tissue samples from patients who present with an esophageal disorder. Identifyi...
What is the current status of trial NCT00260585?
This trial is currently recruiting. The enrollment target is 7,000 participants. The study started on 1999-06. Estimated completion is 2050-12.
What conditions does trial NCT00260585 study?
This clinical trial studies the following conditions: Esophageal Cancer, Hiatal Hernia, Gastroesophageal Reflux Disease (GERD), Esophageal Diseases, Esophageal Achalasia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00260585?
The interventions under investigation include: Survey of client health, personal habits, family history (PROCEDURE), Blood specimen for non-DNA and DNA parts (PROCEDURE), Biopsy of esophageal/stomach tissue, lymph nodes, tumor (PROCEDURE), Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00260585?
This trial is sponsored by University of Pittsburgh, which has 1,082 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00260585 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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