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ClinicalTrials.gov 7 recruiting now official registry

Episodic Migraine clinical trials

Every US clinical trial registered for Episodic Migraine — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

14 US clinical trials · 7 currently recruiting

The research picture

Episodic Migraine has 14 registered US clinical trials, 7 of them open to new participants right now — about 50% of the total.

7
recruiting participants now
50%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
2
top sponsor: Click Therapeutics

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 3 990 participants

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

Merz Therapeutics

NCT07018700

RECRUITING 700 participants

Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine

Hospital Universitari Vall d'Hebron Research Institute

NCT07159750

RECRUITING Phase 2 641 participants

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

Ipsen

NCT06625060

RECRUITING Phase 3 450 participants

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

AbbVie

NCT05711394

RECRUITING Phase 3 315 participants

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine

H. Lundbeck A/S

NCT05897320

RECRUITING NA 60 participants

Chiropractic Care for Episodic Migraine

Brigham and Women's Hospital

NCT06229834

RECRUITING Phase 2 60 participants

Efficacy of Nerve Blocks for Episodic Migraine

Mayo Clinic

NCT05734625

ACTIVE NOT RECRUITING Phase 3 751 participants

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults

Ipsen

NCT06047457

ACTIVE NOT RECRUITING Phase 3 533 participants

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine

Eli Lilly and Company

NCT03432286

COMPLETED Phase 4 621 participants

Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients

Amgen

NCT03927144

COMPLETED Phase 4 580 participants

A Study of Galcanezumab (LY2951742) in Adult Participants With Episodic Migraine

Eli Lilly and Company

NCT05127486

COMPLETED NA 568 participants

Study of Two Digital Therapeutics for the Prevention of Episodic Migraine

Click Therapeutics

NCT05853900

COMPLETED Phase 3 110 participants

Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C)

Click Therapeutics

NCT06004388

COMPLETED Phase 4 76 participants

The Effects of Expectation and Knowledge on Rizatriptan and Placebo Treatment of Acute Migraine Headache

Beth Israel Deaconess Medical Center

NCT00719134

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 6
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Episodic Migraine Trial Landscape

ClinicalTrials.gov lists 14 US studies indexed under Episodic Migraine, and 7 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Episodic Migraine shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Episodic Migraine is led by Click Therapeutics with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Episodic Migraine?

PlainTrial tracks 14 US clinical trials for Episodic Migraine, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Episodic Migraine?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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