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ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Epidermolysis Bullosa: early-phase trial registry

1 of 11 indexed Epidermolysis Bullosa trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 1 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Epidermolysis Bullosa: 11 US clinical trials tracked, 1 recruiting.

Epidermolysis Bullosa is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Abeona Therapeutics, running 3 of these trials.

Enrollment posture brief

Registry condition epidermolysis-bullosa

OPEN 1 | RECR 9% | LATE 3 | EARLY 8 | RANK #1577 | SPON 3

Nearest open-share peer: Advanced Cancers (9% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%Epidermolysis Bullosa (this)9%
Open-enrollment share among volume-matched conditions near Epidermolysis Bullosa

Epidermolysis Bullosa lists 1 open slots (9% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Epidermolysis Bullosa on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Epidermolysis Bullosa is recruiting below its size-band peers.

    1 of 11 indexed trials (9.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Epidermolysis Bullosa research.

    Abeona Therapeutics accounts for 3 of 11 trials (27.3%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Most Epidermolysis Bullosa trials plan to enrol fewer than 100 people.

    Median target enrolment is 12 among the 11 trials that report a genuine target (sentinel values excluded). 11 of those (100%) plan for fewer than 100 participants.

  4. Epidermolysis Bullosa research is mostly interventional.

    11 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 24Phase 33

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 1 8 participants

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

M. Peter Marinkovich

NCT06834035

ACTIVE NOT RECRUITING Phase 3 12 participants

A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients

Abeona Therapeutics

NCT05725018

ACTIVE NOT RECRUITING Phase 3 9 participants

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)

RHEACELL GmbH & Co. KG

NCT05838092

COMPLETED Phase 2 48 participants

Study of Effectiveness and Safety of SD-101 in Participants With Epidermolysis Bullosa

Scioderm

NCT02014376

COMPLETED Phase 1 32 participants

Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs

Masonic Cancer Center, University of Minnesota

NCT01033552

COMPLETED Phase 2 28 participants

A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa

Stanford University

NCT03836001

COMPLETED Early Phase 1 15 participants

Characterization of the Microbiome in Colonized Dystrophic and Junctional Epidermolysis Bullosa Wounds Before and After Use of APR-TD011 ® Spray Solution

Northwestern University

NCT05533866

COMPLETED Phase 2 14 participants

Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients

Jean Yuh Tang

NCT02654483

COMPLETED Phase 1 12 participants

Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa

Abeona Therapeutics

NCT01263379

COMPLETED Phase 3 11 participants

Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Abeona Therapeutics

NCT04227106

COMPLETED Phase 2 8 participants

Study of Alwextin® Cream in Treating Epidermolysis Bullosa

Northwestern University

NCT00825565

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4
Phase 3 3

Named interventions

Most-linked intervention names on Epidermolysis Bullosa records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

EB-101 Biological
1 trials
LZRSE-Col7A1 Engineered Autologous Epidermal Sheets Biological
1 trials
Serlopitant Tablet Drug
1 trials
Alwextin cream Drug
1 trials
Mesenchymal stem cell transplantation Procedure
1 trials
Myeloablative Busulfan Drug
1 trials
VPD-737 Drug
1 trials
Vehicle (SD-101 0%) Drug
1 trials

US sites by state

Facility locations filed on Epidermolysis Bullosa trials. A trial with sites in several states counts in each.

California 7 trials
Illinois 3 trials
Minnesota 2 trials
Massachusetts 2 trials
Washington 1 trials
Texas 1 trials
New Jersey 1 trials
North Carolina 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Epidermolysis Bullosa page

11 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 1 Epidermolysis Bullosa trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Abeona Therapeutics sponsors the most Epidermolysis Bullosa trials on record, review their full trial history before evaluating a specific study. See Abeona Therapeutics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Epidermolysis Bullosa condition card totals 11 registered trials; most-linked intervention EB-101; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.