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Ductal Carcinoma In Situ clinical trials
8 of 16 indexed Ductal Carcinoma In Situ trials are currently recruiting.
16 US clinical trials · 8 currently recruiting
Ductal Carcinoma In Situ is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Xoft, running 2 of these trials.
The research picture
Ductal Carcinoma In Situ has 16 registered US clinical trials, 8 of them open to new participants right now, about 50% of the total.
- 8
- recruiting participants now
- 50%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Xoft
Active & Recent Trials
16 total, page 1 of 1
DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
QuantumLeap Healthcare Collaborative
NCT06075953
EXploring Inflammation and Social deTerminants Study in Breast Cancer Patients
Thomas Jefferson University
NCT07478016
Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT)
RPCR
NCT04985032
Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
UNC Lineberger Comprehensive Cancer Center
NCT06902311
Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions
University of Florida
NCT06903468
Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ
Finn, Olivera, PhD
NCT06218303
Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ
Glendale Adventist Medical Center d/b/a Adventist Health Glendale
NCT05218044
A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients.
Barbara Ann Karmanos Cancer Institute
NCT07095114
Safety and Efficacy Study of the Xoft® Axxent® eBx® IORT System®
Xoft
NCT01644669
Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS
Alliance Foundation Trials
NCT02926911
Intraoperative Radiation Therapy (IORT) in DCIS
Columbia University
NCT03216421
Ruxolitinib for Premalignant Breast Disease
Julie Nangia
NCT02928978
Breast MRI as a Preoperative Tool for DCIS
Memorial Sloan Kettering Cancer Center
NCT00605982
Electronic Xoft Intersociety Brachytherapy Trial: Electronic Brachytherapy (EBT) For Treatment of Early Stage Breast Cancer
Xoft
NCT00742222
Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging
Dartmouth-Hitchcock Medical Center
NCT01060085
Living Well After Breast Surgery
University of Texas at Austin
NCT03834532
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Ductal Carcinoma In Situ Trial Landscape
16 indexed Ductal Carcinoma In Situ studies · 8 recruiting (50%).
Phase mix: 1 late (III/IV) vs 4 early (I/II).
Top sponsor: Xoft (2 trials), 9 others listed. 16 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Ductal Carcinoma In Situ?
PlainTrial tracks 16 US clinical trials for Ductal Carcinoma In Situ, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Ductal Carcinoma In Situ?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.