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ClinicalTrials.gov 2 recruiting now official registry

Ductal Breast Carcinoma in Situ clinical trials

2 of 12 indexed Ductal Breast Carcinoma in Situ trials are currently recruiting.

12 US clinical trials · 2 currently recruiting

Ductal Breast Carcinoma in Situ is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

The research picture

Ductal Breast Carcinoma in Situ has 12 registered US clinical trials, 2 of them open to new participants right now, about 17% of the total.

2
recruiting participants now
17%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: M.D. Anderson Cancer Center
Phase 27Phase 31

Active & Recent Trials

12 total, page 1 of 1

RECRUITING Phase 2 144 participants

5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer

University of Utah

NCT06961955

RECRUITING NA 50 participants

Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma

Stanford University

NCT03909282

ACTIVE NOT RECRUITING NA 368 participants

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

ECOG-ACRIN Cancer Research Group

NCT02352883

ACTIVE NOT RECRUITING Phase 2 301 participants

Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast Cancer

M.D. Anderson Cancer Center

NCT01266642

ACTIVE NOT RECRUITING Phase 2 200 participants

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

M.D. Anderson Cancer Center

NCT01245712

ACTIVE NOT RECRUITING Phase 2 156 participants

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Northwestern University

NCT04009044

ACTIVE NOT RECRUITING Phase 3 86 participants

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Alliance for Clinical Trials in Oncology

NCT01905046

ACTIVE NOT RECRUITING NA 51 participants

Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants

M.D. Anderson Cancer Center

NCT03546972

ACTIVE NOT RECRUITING NA 4 participants

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Ohio State University Comprehensive Cancer Center

NCT04537312

COMPLETED Phase 2 200 participants

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery

Rutgers, The State University of New Jersey

NCT02526498

COMPLETED Phase 2 57 participants

Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT01869764

COMPLETED Phase 2 52 participants

Effect of Omega 3 on Atrophic Vaginitis in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT02150525

Phase Distribution

PhaseTrial count
Phase 2 7
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ductal Breast Carcinoma in Situ Trial Landscape

12 indexed Ductal Breast Carcinoma in Situ studies · 2 recruiting (17%).

Phase mix: 1 late (III/IV) vs 7 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (3 trials), 8 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ductal Breast Carcinoma in Situ?

PlainTrial tracks 12 US clinical trials for Ductal Breast Carcinoma in Situ, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ductal Breast Carcinoma in Situ?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.