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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Ductal Breast Carcinoma in Situ: early-phase trial registry

2 of 12 indexed Ductal Breast Carcinoma in Situ trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 2 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Ductal Breast Carcinoma in Situ: 12 US clinical trials tracked, 2 recruiting.

Ductal Breast Carcinoma in Situ is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition ductal-breast-carcinoma-in-situ

OPEN 2 | RECR 17% | LATE 1 | EARLY 7 | RANK #1429 | SPON 3

Nearest open-share peer: Acute Renal Failure (17% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Ductal Breast Carcinoma (th…17%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Ductal Breast Carcinoma in Situ

Ductal Breast Carcinoma in Situ lists 2 open slots (17% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ductal Breast Carcinoma in Situ on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ductal Breast Carcinoma in Situ is recruiting below its size-band peers.

    2 of 12 indexed trials (16.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Ductal Breast Carcinoma in Situ research.

    M.D. Anderson Cancer Center accounts for 3 of 12 trials (25%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ductal Breast Carcinoma in Situ enrolment sits around 144 participants.

    Median target enrolment is 144 among the 12 trials that report a genuine target (sentinel values excluded). 6 of those (50%) plan for fewer than 100 participants.

  4. Ductal Breast Carcinoma in Situ research is mostly interventional.

    12 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 27Phase 31

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 2 144 participants

5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer

University of Utah

NCT06961955

RECRUITING NA 50 participants

Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma

Stanford University

NCT03909282

ACTIVE NOT RECRUITING NA 368 participants

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

ECOG-ACRIN Cancer Research Group

NCT02352883

ACTIVE NOT RECRUITING Phase 2 301 participants

Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast Cancer

M.D. Anderson Cancer Center

NCT01266642

ACTIVE NOT RECRUITING Phase 2 200 participants

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

M.D. Anderson Cancer Center

NCT01245712

ACTIVE NOT RECRUITING Phase 2 156 participants

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Northwestern University

NCT04009044

ACTIVE NOT RECRUITING Phase 3 86 participants

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Alliance for Clinical Trials in Oncology

NCT01905046

ACTIVE NOT RECRUITING NA 51 participants

Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants

M.D. Anderson Cancer Center

NCT03546972

ACTIVE NOT RECRUITING NA 4 participants

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Ohio State University Comprehensive Cancer Center

NCT04537312

COMPLETED Phase 2 200 participants

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery

Rutgers, The State University of New Jersey

NCT02526498

COMPLETED Phase 2 57 participants

Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT01869764

COMPLETED Phase 2 52 participants

Effect of Omega 3 on Atrophic Vaginitis in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT02150525

Phase Distribution

PhaseTrial count
Phase 2 7
Phase 3 1

Named interventions

Most-linked intervention names on Ductal Breast Carcinoma in Situ records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

placebo Other
3 trials
Questionnaire Administration Other
3 trials
Accelerated Partial Breast Irradiation Radiation
2 trials
Radiation Therapy Radiation
2 trials
Quality-of-Life Assessment Other
2 trials
Questionnaire administration Behavioral
1 trials
omega-3 fatty acid Drug
1 trials
RNSM Device
1 trials

US sites by state

Facility locations filed on Ductal Breast Carcinoma in Situ trials. A trial with sites in several states counts in each.

Ohio 4 trials
California 4 trials
Texas 3 trials
Utah 2 trials
New York 2 trials
North Carolina 2 trials
Indiana 2 trials
Illinois 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ductal Breast Carcinoma in Situ page

12 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ductal Breast Carcinoma in Situ condition card totals 12 registered trials; most-linked intervention placebo; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.