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Dry Eye Syndromes clinical trials
Every US clinical trial registered for Dry Eye Syndromes — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
19 US clinical trials · 1 currently recruiting
The research picture
Dry Eye Syndromes has 19 registered US clinical trials, 1 of them open to new participants right now — about 5% of the total.
- 1
- recruiting participants now
- 5%
- of trials open to enrollment
- 5
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Allergan
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Clinical Applications of Advanced Ophthalmic Imaging
University of Miami
NCT03135327
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals
Western University of Health Sciences
NCT05763940
Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease
Allergan
NCT01459588
A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye.
Seikagaku Corporation
NCT02205840
Diagnostic Evaluation of the Tear Film
TearScience
NCT00761917
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Patients With Dry Eye
Kubota Vision
NCT01027013
CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)
Novaliq
NCT02617667
Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal Neurostimulation
Allergan
NCT02910713
A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye
Seikagaku Corporation
NCT01558999
TearLab Refractive Surgery Dry Eye Study
TearLab Corporation
NCT01176045
TrueTear in Sjogren's Disease Patients
University of Pennsylvania
NCT03719885
Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis®
Allergan
NCT02554981
Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD
Lumenis Be
NCT02621593
ACCURATE Study for Subjects With Dry Eyes
The Eye Centers of Racine and Kenosha
NCT04237012
Dry Eye Assessment and Management: Feasibility Study
Asbell, Penny, M.D.
NCT01102257
Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease
Eye Surgeons of Indiana
NCT04413279
Corneal Epithelial Stem Cells and Dry Eye Disease
Sloan W. Rush, MD
NCT03302273
Topical Naloxone to Diagnose Ocular Pain
Seema Capoor
NCT04454281
Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-005)
Sirion Therapeutics
NCT00502073
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dry Eye Syndromes Trial Landscape
ClinicalTrials.gov lists 19 US studies indexed under Dry Eye Syndromes, and 1 of those are currently open to recruitment — roughly 5% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Dry Eye Syndromes shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Dry Eye Syndromes is led by Allergan with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dry Eye Syndromes?
PlainTrial tracks 19 US clinical trials for Dry Eye Syndromes, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dry Eye Syndromes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.