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ClinicalTrials.gov 5 recruiting now official registry

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified clinical trials

5 of 10 indexed Diffuse Large B-Cell Lymphoma, Not Otherwise Specified trials are currently recruiting.

10 US clinical trials · 5 currently recruiting

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 3 of these trials.

The research picture

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified has 10 registered US clinical trials, 5 of them open to new participants right now, about 50% of the total.

5
recruiting participants now
50%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: University of Washington
Phase 14Phase 24

Active & Recent Trials

10 total, page 1 of 1

RECRUITING Phase 1 120 participants

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Poseida Therapeutics

NCT06014762

RECRUITING Phase 2 120 participants

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

Academic and Community Cancer Research United

NCT06238648

RECRUITING Phase 1 56 participants

Polatuzumab Vedotin and Combination Chemotherapy With or Without Glofitamab for the Treatment of Untreated Aggressive Large B-cell Lymphoma

University of Washington

NCT04231877

RECRUITING NA 40 participants

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

Hua-Jay J Cherng, MD

NCT06693830

RECRUITING Phase 2 18 participants

Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma

University of Washington

NCT07097363

ACTIVE NOT RECRUITING Phase 2 363 participants

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas

National Cancer Institute (NCI)

NCT03984448

ACTIVE NOT RECRUITING NA 73 participants

Nanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large B-Cell Lymphoma

Ohio State University Comprehensive Cancer Center

NCT03656835

ACTIVE NOT RECRUITING Phase 2 54 participants

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

National Cancer Institute (NCI)

NCT03038672

ACTIVE NOT RECRUITING Phase 1 23 participants

Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma

University of Washington

NCT04257578

COMPLETED Phase 1 12 participants

Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma

Northwestern University

NCT03742258

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Trial Landscape

10 indexed Diffuse Large B-Cell Lymphoma, Not Otherwise Specified studies · 5 recruiting (50%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: University of Washington (3 trials), 6 others listed. 10 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified?

PlainTrial tracks 10 US clinical trials for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.