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RECRUITING Phase 1

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

NCT06014762 · View on ClinicalTrials.gov ↗

Study Summary

Phase 1 study comprised of open-label, dose escalation and expansion cohort study of P-CD19CD20-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed/refractory B cell malignancies

Interventions

  • DRUG Rimiducid
  • BIOLOGICAL P-CD19CD20-ALLO1

Study Locations (17)

California

  • University of California San Diego — La Jolla
  • Loma Linda University Cancer Center — Loma Linda
  • Cedars-Sinai Medical Center — Los Angeles

Louisiana

  • Our Lady of the Lake Hospital — Baton Rouge
  • Ochsner Clinic Foundation — New Orleans

Florida

  • Advent Health Orlando — Orlando

Indiana

  • Indiana University — Indianapolis

Michigan

  • Wayne State - Karmanos Cancer Institute — Detroit

New York

  • NYU Grossman School of Medicine — New York

North Carolina

  • UNC Lineberger Comprehensive Cancer Center — Chapel Hill

Ohio

  • University of Cincinnati — Cincinnati

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2024-04-16
Est. Completion 2041-03
Phase Phase 1

Sponsor

Poseida Therapeutics

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06014762

The ClinicalTrials.gov registry entry for NCT06014762 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Poseida Therapeutics, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 10 conditions, with High-grade B-cell Lymphoma appearing as the primary indexed condition, and to 2 interventions — of which Rimiducid is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06014762 reports 17 study locations spanning 14 distinct geographic areas — top geographies include California, Louisiana, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06014762 about?

NCT06014762 is a clinical study titled "P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies". Phase 1 study comprised of open-label, dose escalation and expansion cohort study of P-CD19CD20-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed/refractory B cell malignancies

What is the current status of trial NCT06014762?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2024-04-16. Estimated completion is 2041-03.

What conditions does trial NCT06014762 study?

This clinical trial studies the following conditions: High-grade B-cell Lymphoma, DLBCL, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, DLBCL - Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06014762?

The interventions under investigation include: Rimiducid (DRUG), P-CD19CD20-ALLO1 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06014762?

This trial is sponsored by Poseida Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06014762 being conducted?

This trial has 17 study locations across California, Florida, Indiana, Louisiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial