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ClinicalTrials.gov 10 recruiting now early-phase tilt

COVID-19 Infection: early-phase trial registry

10 of 22 indexed COVID-19 Infection trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 10 currently recruiting · #756 of 28,707 conditions by registered trial count

COVID-19 Infection: 22 US clinical trials tracked, 10 recruiting.

COVID-19 Infection is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 12 of these trials.

Enrollment posture brief

Registry condition covid-19-infection

OPEN 10 | RECR 45% | LATE 1 | EARLY 3 | RANK #756 | SPON 12

Nearest open-share peer: Acute Stroke (45% recruiting · 11 trials)

Advanced Melanoma63.6%COVID-19 Infection (this)45%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near COVID-19 Infection

COVID-19 Infection lists 10 open slots (45% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for COVID-19 Infection on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. COVID-19 Infection is recruiting above its size-band peers.

    10 of 22 indexed trials (45.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates COVID-19 Infection research.

    M.D. Anderson Cancer Center accounts for 12 of 22 trials (54.5%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical COVID-19 Infection enrolment sits around 549 participants.

    Median target enrolment is 549 among the 22 trials that report a genuine target (sentinel values excluded). 5 of those (22.7%) plan for fewer than 100 participants.

  4. COVID-19 Infection research leans observational.

    6 interventional and 16 observational studies make up this index (27.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 22Phase 31

Open and recent trials

22 total, page 1 of 1

RECRUITING 20,000 participants

Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce

M.D. Anderson Cancer Center

NCT04491292

RECRUITING 5,000 participants

Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04582903

RECRUITING 5,000 participants

Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health

University of California, San Diego

NCT05553743

RECRUITING 1,152 participants

Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic

M.D. Anderson Cancer Center

NCT04474301

RECRUITING 600 participants

Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery

M.D. Anderson Cancer Center

NCT04169542

RECRUITING 600 participants

The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors

M.D. Anderson Cancer Center

NCT04551378

RECRUITING Phase 3 300 participants

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

Pfizer

NCT07013474

RECRUITING 250 participants

The Impact of COVID-19 on Pulmonary Procedures

M.D. Anderson Cancer Center

NCT05022446

RECRUITING Phase 2 80 participants

A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia

City of Hope Medical Center

NCT05672355

RECRUITING Phase 1 70 participants

Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia

M.D. Anderson Cancer Center

NCT04565665

ACTIVE NOT RECRUITING 15,240 participants

Impact of COVID-19 on GU Disease

Icahn School of Medicine at Mount Sinai

NCT04761107

ACTIVE NOT RECRUITING 13,378 participants

Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic

M.D. Anderson Cancer Center

NCT04500600

ACTIVE NOT RECRUITING 1,877 participants

NCI COVID-19 in Cancer Patients, NCCAPS Study

National Cancer Institute (NCI)

NCT04387656

ACTIVE NOT RECRUITING 1,242 participants

Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors

M.D. Anderson Cancer Center

NCT04447222

ACTIVE NOT RECRUITING 549 participants

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Children's Oncology Group

NCT05228275

ACTIVE NOT RECRUITING 274 participants

Well-being in Cancer Patients With Neuropathy During COVID-19 Who Participated in Prior Clinical Trials

M.D. Anderson Cancer Center

NCT04650178

ACTIVE NOT RECRUITING NA 107 participants

Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic

M.D. Anderson Cancer Center

NCT05102656

ACTIVE NOT RECRUITING NA 100 participants

Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic

M.D. Anderson Cancer Center

NCT04482647

ACTIVE NOT RECRUITING Phase 2 63 participants

SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer

GeoVax

NCT04977024

ACTIVE NOT RECRUITING 1 participants

A Study to Learn About How Well Yearly Updates to the COVID-19 Vaccine Work to Protect People From COVID-19 and How Much Money People Spend on Healthcare for COVID-19

Pfizer

NCT06923137

COMPLETED 223 participants

Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer

M.D. Anderson Cancer Center

NCT05058339

COMPLETED 72 participants

PREDICT: A PBRN Feasibility Study on COVID-19 Screening in Dental Practice

Rutgers, The State University of New Jersey

NCT05123742

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on COVID-19 Infection records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
8 trials
Survey Administration Other
6 trials
Quality-of-Life Assessment Other
6 trials
Biospecimen Collection Procedure
3 trials
Best Practice Other
2 trials
COVID-19 Testing Diagnostic test
1 trials
BNT162b2 Drug
1 trials
Synthetic MVA-based SARS-CoV-2 Vaccine GEO-CM04S1 Biological
1 trials

US sites by state

Facility locations filed on COVID-19 Infection trials. A trial with sites in several states counts in each.

Texas 12 trials
California 5 trials
New York 3 trials
Maryland 3 trials
Massachusetts 2 trials
Illinois 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this COVID-19 Infection page

22 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This COVID-19 Infection condition card totals 22 registered trials; most-linked intervention Questionnaire Administration; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.