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COVID-19 Infection clinical trials
Every US clinical trial registered for COVID-19 Infection — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
22 US clinical trials · 10 currently recruiting
The research picture
COVID-19 Infection has 22 registered US clinical trials, 10 of them open to new participants right now — about 45% of the total.
- 10
- recruiting participants now
- 45%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 12
- top sponsor: M.D. Anderson Cancer Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce
M.D. Anderson Cancer Center
NCT04491292
Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04582903
Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health
University of California, San Diego
NCT05553743
Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04474301
Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery
M.D. Anderson Cancer Center
NCT04169542
The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04551378
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
Pfizer
NCT07013474
The Impact of COVID-19 on Pulmonary Procedures
M.D. Anderson Cancer Center
NCT05022446
A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia
City of Hope Medical Center
NCT05672355
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
M.D. Anderson Cancer Center
NCT04565665
Impact of COVID-19 on GU Disease
Icahn School of Medicine at Mount Sinai
NCT04761107
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04500600
NCI COVID-19 in Cancer Patients, NCCAPS Study
National Cancer Institute (NCI)
NCT04387656
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
M.D. Anderson Cancer Center
NCT04447222
Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer
Children's Oncology Group
NCT05228275
Well-being in Cancer Patients With Neuropathy During COVID-19 Who Participated in Prior Clinical Trials
M.D. Anderson Cancer Center
NCT04650178
Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT05102656
Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic
M.D. Anderson Cancer Center
NCT04482647
SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer
GeoVax
NCT04977024
A Study to Learn About How Well Yearly Updates to the COVID-19 Vaccine Work to Protect People From COVID-19 and How Much Money People Spend on Healthcare for COVID-19
Pfizer
NCT06923137
Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer
M.D. Anderson Cancer Center
NCT05058339
PREDICT: A PBRN Feasibility Study on COVID-19 Screening in Dental Practice
Rutgers, The State University of New Jersey
NCT05123742
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the COVID-19 Infection Trial Landscape
ClinicalTrials.gov lists 22 US studies indexed under COVID-19 Infection, and 10 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for COVID-19 Infection shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for COVID-19 Infection is led by M.D. Anderson Cancer Center with 12 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for COVID-19 Infection?
PlainTrial tracks 22 US clinical trials for COVID-19 Infection, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for COVID-19 Infection?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.