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ClinicalTrials.gov 5 recruiting now official registry

Colon Adenocarcinoma clinical trials

5 of 12 indexed Colon Adenocarcinoma trials are currently recruiting.

12 US clinical trials · 5 currently recruiting

Colon Adenocarcinoma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 2 of these trials.

The research picture

Colon Adenocarcinoma has 12 registered US clinical trials, 5 of them open to new participants right now, about 42% of the total.

5
recruiting participants now
42%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
2
top sponsor: National Cancer Institute (NCI)
Phase 12Phase 24Phase 34

Active & Recent Trials

12 total, page 1 of 1

RECRUITING 2,700 participants

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

Mainz Biomed

NCT06864338

RECRUITING Phase 3 477 participants

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Merck Sharp & Dohme

NCT06997497

RECRUITING Phase 2 80 participants

Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study

University of Kansas Medical Center

NCT06017141

RECRUITING Phase 1 22 participants

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

University of California, Irvine

NCT04920032

RECRUITING Phase 3 20 participants

Evaluating Novel Therapies in ctDNA Positive GI Cancers

Georgetown University

NCT05482516

ACTIVE NOT RECRUITING Phase 3 2,431 participants

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

National Cancer Institute (NCI)

NCT00217737

ACTIVE NOT RECRUITING 818 participants

Young-Onset Colorectal Cancer

M.D. Anderson Cancer Center

NCT02863107

ACTIVE NOT RECRUITING Phase 3 712 participants

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

National Cancer Institute (NCI)

NCT02912559

ACTIVE NOT RECRUITING Phase 2 635 participants

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

NRG Oncology

NCT04068103

ACTIVE NOT RECRUITING Phase 2 48 participants

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

University of Colorado, Denver

NCT04963283

ACTIVE NOT RECRUITING Phase 2 1 participants

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Alliance for Clinical Trials in Oncology

NCT05710406

COMPLETED Phase 1 42 participants

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Roswell Park Cancer Institute

NCT02393755

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Colon Adenocarcinoma Trial Landscape

12 indexed Colon Adenocarcinoma studies · 5 recruiting (42%).

Phase mix: 4 late (III/IV) vs 6 early (I/II).

Top sponsor: National Cancer Institute (NCI) (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Colon Adenocarcinoma?

PlainTrial tracks 12 US clinical trials for Colon Adenocarcinoma, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Colon Adenocarcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.