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ClinicalTrials.gov 5 recruiting now full pipeline small index

Colon Adenocarcinoma: full-pipeline trial registry

5 of 12 indexed Colon Adenocarcinoma trials are currently recruiting.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Colon Adenocarcinoma: 12 US clinical trials tracked, 5 recruiting.

Colon Adenocarcinoma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 2 of these trials.

Enrollment posture brief

Registry condition colon-adenocarcinoma

OPEN 5 | RECR 42% | LATE 4 | EARLY 6 | RANK #1429 | SPON 2

Nearest open-share peer: Adiposity (42% recruiting · 12 trials)

Colon Adenocarcinoma (this)42%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Colon Adenocarcinoma

Colon Adenocarcinoma lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Colon Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Colon Adenocarcinoma is recruiting below its size-band peers.

    5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Colon Adenocarcinoma research.

    National Cancer Institute (NCI) accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Colon Adenocarcinoma enrolment sits around 477 participants.

    Median target enrolment is 477 among the 12 trials that report a genuine target (sentinel values excluded). 6 of those (50%) plan for fewer than 100 participants.

  4. Colon Adenocarcinoma research is mostly interventional.

    10 interventional and 2 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 24Phase 34

Open and recent trials

12 total, page 1 of 1

RECRUITING 2,700 participants

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

Mainz Biomed

NCT06864338

RECRUITING Phase 3 477 participants

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Merck Sharp & Dohme

NCT06997497

RECRUITING Phase 2 80 participants

Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study

University of Kansas Medical Center

NCT06017141

RECRUITING Phase 1 22 participants

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

University of California, Irvine

NCT04920032

RECRUITING Phase 3 20 participants

Evaluating Novel Therapies in ctDNA Positive GI Cancers

Georgetown University

NCT05482516

ACTIVE NOT RECRUITING Phase 3 2,431 participants

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

National Cancer Institute (NCI)

NCT00217737

ACTIVE NOT RECRUITING 818 participants

Young-Onset Colorectal Cancer

M.D. Anderson Cancer Center

NCT02863107

ACTIVE NOT RECRUITING Phase 3 712 participants

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

National Cancer Institute (NCI)

NCT02912559

ACTIVE NOT RECRUITING Phase 2 635 participants

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

NRG Oncology

NCT04068103

ACTIVE NOT RECRUITING Phase 2 48 participants

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

University of Colorado, Denver

NCT04963283

ACTIVE NOT RECRUITING Phase 2 1 participants

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Alliance for Clinical Trials in Oncology

NCT05710406

COMPLETED Phase 1 42 participants

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Roswell Park Cancer Institute

NCT02393755

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 4

Named interventions

Most-linked intervention names on Colon Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
4 trials
Oxaliplatin Drug
3 trials
Fluorouracil Drug
3 trials
Leucovorin Calcium Drug
2 trials
Questionnaire Administration Other
2 trials
Leucovorin Drug
2 trials
Cetuximab Biological
2 trials
Atezolizumab Drug
2 trials

US sites by state

Facility locations filed on Colon Adenocarcinoma trials. A trial with sites in several states counts in each.

California 6 trials
Arizona 3 trials
Arkansas 3 trials
Alaska 3 trials
New Jersey 2 trials
Alabama 2 trials
Virginia 1 trials
Utah 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Colon Adenocarcinoma page

12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Colon Adenocarcinoma condition card totals 12 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.