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NCT04068103 · ClinicalTrials.gov registry record · Phase 2
Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery
A Phase 2 study of Colon Adenocarcinoma and Stage IIA Colon Cancer AJCC v8, sponsored by NRG Oncology.
- Active
- Registry status
- Phase 2
- Development phase
- 635
- Enrollment target
- 20
- Study locations
NCT04068103 is a Phase 2 study of Colon Adenocarcinoma and Stage IIA Colon Cancer AJCC v8 that is active but no longer recruiting, run by NRG Oncology. The registered enrollment target is 635 participants, roughly in line with the 668-participant average among 11 other Colon Adenocarcinoma trials with a reported enrollment target. The trial reports 20 study locations across 5 states.
The verdict
NCT04068103, a Phase 2 study of Colon Adenocarcinoma and Stage IIA Colon Cancer AJCC v8, is active but no longer recruiting, sponsored by NRG Oncology.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 635 participants
- Enrollment target
- 20
- Study locations
Study Summary
This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of cancer that remain after surgery. However, this cancer, if detected, cannot be found on other tests usually used to find cancer, as it is too small. Testing for ctDNA levels may help identify patients with colon cancer after surgery who do benefit, and those who do not benefit, from receiving chemotherapy.
Conditions Studied
Interventions
- DRUG Capecitabine
- DRUG Fluorouracil
- DRUG Leucovorin
- DRUG Oxaliplatin
- DRUG Leucovorin Calcium
Study Locations (20)
Alaska
- Anchorage Associates in Radiation Medicine - Anchorage
- Anchorage Radiation Therapy Center - Anchorage
- Alaska Breast Care and Surgery LLC - Anchorage
- Alaska Oncology and Hematology LLC - Anchorage
- Alaska Women's Cancer Care - Anchorage
- Anchorage Oncology Centre - Anchorage
- Katmai Oncology Group - Anchorage
- Providence Alaska Medical Center - Anchorage
- Fairbanks Memorial Hospital - Fairbanks
Arizona
- Kingman Regional Medical Center - Kingman
- Cancer Center at Saint Joseph's - Phoenix
- Banner University Medical Center - Tucson - Tucson
- University of Arizona Cancer Center-North Campus - Tucson
Arkansas
- Mercy Hospital Fort Smith - Fort Smith
- CHI Saint Vincent Cancer Center Hot Springs - Hot Springs
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro - Jonesboro
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
- University of South Alabama Mitchell Cancer Institute - Mobile
California
- Kaiser Permanente-Anaheim - Anaheim
- Mission Hope Medical Oncology - Arroyo Grande - Arroyo Grande
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 635 participants |
| Start Date | 2019-12-16 |
| Est. Completion | 2026-06-21 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04068103
The ClinicalTrials.gov registry entry for NCT04068103 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 635 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 668-participant average among 11 other Colon Adenocarcinoma trials with a reported enrollment target. The listed sponsor is NRG Oncology, which has 64 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Colon Adenocarcinoma appearing as the primary indexed condition, and to 5 interventions - of which Capecitabine is the first listed.
NCT04068103 reports 20 study locations spanning 5 distinct geographic areas - top geographies include Alaska, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT04068103 about?
NCT04068103 is a clinical study titled "Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery". This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood mea...
What is the current status of trial NCT04068103?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 635 participants. The study started on 2019-12-16. Estimated completion is 2026-06-21.
What conditions does trial NCT04068103 study?
This clinical trial studies the following conditions: Colon Adenocarcinoma, Stage IIA Colon Cancer AJCC v8.
What interventions are being tested in trial NCT04068103?
The interventions under investigation include: Capecitabine (DRUG), Fluorouracil (DRUG), Leucovorin (DRUG), Oxaliplatin (DRUG), Leucovorin Calcium (DRUG).
Who is sponsoring clinical trial NCT04068103?
This trial is sponsored by NRG Oncology, which has 64 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04068103 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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