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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Clostridium Difficile Infection: early-phase trial registry

5 of 14 indexed Clostridium Difficile Infection trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 5 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Clostridium Difficile Infection: 14 US clinical trials tracked, 5 recruiting.

Clostridium Difficile Infection is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Finch Research and Development, running 1 of these trials.

Enrollment posture brief

Registry condition clostridium-difficile-infection

OPEN 5 | RECR 36% | LATE 1 | EARLY 8 | RANK #1230 | SPON 1

Nearest open-share peer: Attention (36% recruiting · 14 trials)

Clostridium Difficile In (th…36%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Clostridium Difficile Infection

Clostridium Difficile Infection lists 5 open slots (36% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Clostridium Difficile Infection on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Clostridium Difficile Infection is recruiting below its size-band peers.

    5 of 14 indexed trials (35.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Clostridium Difficile Infection trials is spread across many organizations.

    Finch Research and Development accounts for 1 of 14 trials (7.1%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Clostridium Difficile Infection enrolment sits around 210 participants.

    Median target enrolment is 210 among the 14 trials that report a genuine target (sentinel values excluded). 3 of those (21.4%) plan for fewer than 100 participants.

  4. Clostridium Difficile Infection research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 27Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING 4,000 participants

Fecal Microbiota Transplant National Registry

American Gastroenterological Association

NCT03325855

RECRUITING NA 500 participants

Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile

Krunal Patel

NCT03562741

RECRUITING Phase 2 260 participants

Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)

University of Virginia

NCT04305769

RECRUITING Phase 2 176 participants

Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients

Riverside University Health System Medical Center

NCT07221370

RECRUITING NA 100 participants

Fecal Microbiota Transplantation for C Diff Infection

Englewood Hospital and Medical Center

NCT01905709

COMPLETED 148,549 participants

Protocol for Admission Toxigenic C. Difficile Surveillance

Endeavor Health

NCT04014608

COMPLETED NA 2,461 participants

Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile Strains

Meridian Bioscience

NCT02968758

COMPLETED Phase 2 272 participants

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

Rebiotix

NCT02589847

COMPLETED Phase 2 210 participants

Study of CB-183,315 in Participants With Clostridium Difficile Infection

Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT01085591

COMPLETED Phase 2 132 participants

Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile Infection

Finch Research and Development

NCT03497806

COMPLETED Phase 4 104 participants

Oral Vancomycin to Prevent Recurrent C Difficile Infection With Antibiotics

University of Nevada, Reno

NCT03466502

COMPLETED Phase 2 84 participants

Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)

Actelion

NCT01222702

COMPLETED Phase 1 7 participants

Vancomycin for the Treatment of NAAT(+)/Toxin(-) C. Difficile

Medical College of Wisconsin

NCT03827447

COMPLETED Phase 2 1 participants

The GRAFT Study: Gut RecolonizAtion by Fecal Transplantation

University of Wisconsin, Madison

NCT03621657

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7
Phase 4 1

Named interventions

Most-linked intervention names on Clostridium Difficile Infection records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Vancomycin Drug
2 trials
Placebo Drug
2 trials
CB-183,315 Drug
1 trials
Placebo-matching vancomycin Drug
1 trials
Placebo-matching cadazolid Drug
1 trials
Cadazolid Drug
1 trials
CP101 Biological
1 trials
Vancomycin Oral Capsule Drug
1 trials

US sites by state

Facility locations filed on Clostridium Difficile Infection trials. A trial with sites in several states counts in each.

Illinois 6 trials
Florida 5 trials
Michigan 4 trials
Idaho 4 trials
Georgia 4 trials
California 4 trials
Wisconsin 3 trials
Massachusetts 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Clostridium Difficile Infection page

14 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Clostridium Difficile Infection condition card totals 14 registered trials; most-linked intervention Vancomycin; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.