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Clostridium Difficile Infection clinical trials
5 of 14 indexed Clostridium Difficile Infection trials are currently recruiting.
14 US clinical trials · 5 currently recruiting
Clostridium Difficile Infection is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Finch Research and Development, running 1 of these trials.
The research picture
Clostridium Difficile Infection has 14 registered US clinical trials, 5 of them open to new participants right now, about 36% of the total.
- 5
- recruiting participants now
- 36%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Finch Research and Development
Active & Recent Trials
14 total, page 1 of 1
Fecal Microbiota Transplant National Registry
American Gastroenterological Association
NCT03325855
Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
Krunal Patel
NCT03562741
Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)
University of Virginia
NCT04305769
Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients
Riverside University Health System Medical Center
NCT07221370
Fecal Microbiota Transplantation for C Diff Infection
Englewood Hospital and Medical Center
NCT01905709
Protocol for Admission Toxigenic C. Difficile Surveillance
Endeavor Health
NCT04014608
Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile Strains
Meridian Bioscience
NCT02968758
Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection
Rebiotix
NCT02589847
Study of CB-183,315 in Participants With Clostridium Difficile Infection
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT01085591
Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile Infection
Finch Research and Development
NCT03497806
Oral Vancomycin to Prevent Recurrent C Difficile Infection With Antibiotics
University of Nevada, Reno
NCT03466502
Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)
Actelion
NCT01222702
Vancomycin for the Treatment of NAAT(+)/Toxin(-) C. Difficile
Medical College of Wisconsin
NCT03827447
The GRAFT Study: Gut RecolonizAtion by Fecal Transplantation
University of Wisconsin, Madison
NCT03621657
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Clostridium Difficile Infection Trial Landscape
14 indexed Clostridium Difficile Infection studies · 5 recruiting (36%).
Phase mix: 1 late (III/IV) vs 8 early (I/II).
Top sponsor: Finch Research and Development (1 trial), 9 others listed. 14 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Clostridium Difficile Infection?
PlainTrial tracks 14 US clinical trials for Clostridium Difficile Infection, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Clostridium Difficile Infection?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.