Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04014608 · ClinicalTrials.gov registry record
Protocol for Admission Toxigenic C. Difficile Surveillance
A clinical trial of Clostridium Difficile Infection, sponsored by Endeavor Health.
- Completed
- Registry status
- 148,549
- Enrollment target
- 1
- Study location
NCT04014608: Completed study of Clostridium Difficile Infection, sponsored by Endeavor Health.
NCT04014608 is a study of Clostridium Difficile Infection that has completed, run by Endeavor Health. The registered enrollment target is 148,549 participants, above the 639-participant average among 13 other Clostridium Difficile Infection trials with a reported enrollment target (23147% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04014608, a study of Clostridium Difficile Infection, has completed, sponsored by Endeavor Health.
- COMPLETED
- Registry status
- 148,549 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Clostridioides (formerly Clostridium) difficile Infection (CDI) is a persistent healthcare issue. In the US, CDI is the most common infectious cause of hospital-onset (HO) diarrhea. Objective: Assess the impact of admission testing for toxigenic C. difficile colonization on the incidence of clinical disease. Design: Pragmatic stepped-wedge Infection Control initiative. Setting: NorthShore University HealthSystem (NorthShore) is a four-hospital system near Chicago, Illinois. Patients: All patients admitted to the four hospitals during the initiative. Interventions: From September 2017 through August 2018 the investigators conducted a quality improvement program where admitted patients had a peri-rectal swab tested for toxigenic C. difficile. All colonized patients were placed in contact precautions. Measurements: The investigators tested admissions who: i) had been hospitalized within two months, ii) had a past C. difficile positive test, and/or iii) were in a long-term care facility within six months. The investigators measured compliance with all other measures to reduce the incidence of HO-CDI. Limitations: This was not a randomized controlled trial, and multiple prevention interventions were in place at the time of the admission surveillance initiative.
Primary Outcome
An altered incidence of this hospital acquired infection
Conditions Studied
Interventions
- OTHER Standard Practice to Prevent Hospital Onset CDI
Study Locations (1)
Illinois
- NorthShore University HealthSystem Research Institute - Evanston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 148,549 participants |
| Start Date | 2016-07-01 |
| Est. Completion | 2018-12-31 |
What the finished NCT04014608 record still lists
NCT04014608 is an observational study that tracks outcomes without assigning an intervention. Its 148,549 participants enrollment target places it among the larger protocols in the corpus, above the 639-participant average among 13 other Clostridium Difficile Infection trials with a reported enrollment target (23147% higher).
The record links to 1 condition, with Clostridium Difficile Infection appearing as the primary indexed condition, and to 1 intervention - of which Standard Practice to Prevent Hospital Onset CDI is the first listed.
NCT04014608 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04014608 about?
NCT04014608 is a clinical study titled "Protocol for Admission Toxigenic C. Difficile Surveillance". Background: Clostridioides (formerly Clostridium) difficile Infection (CDI) is a persistent healthcare issue. In the US, CDI is the most common infectious cause of hospital-onset (HO) diarrhea. Objective: Assess the impact of admission testing for toxigenic C. difficile colonization on the incidenc...
What is the current status of trial NCT04014608?
This trial is currently completed. The enrollment target is 148,549 participants. The study started on 2016-07-01. Estimated completion is 2018-12-31.
What conditions does trial NCT04014608 study?
This clinical trial studies the following conditions: Clostridium Difficile Infection.
What interventions are being tested in trial NCT04014608?
The interventions under investigation include: Standard Practice to Prevent Hospital Onset CDI (OTHER).
Who is sponsoring clinical trial NCT04014608?
This trial is sponsored by Endeavor Health, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04014608 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Clostridium Difficile Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04014608's enrollment target sits among peer trials
148,549 1st of 13 higher than 13 of 13 other Clostridium Difficile Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Clostridium Difficile Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
RECRUITING · NA
-
Fecal Microbiota Transplantation for C Diff Infection
RECRUITING · NA
-
Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)
RECRUITING · Phase 2
-
Fecal Microbiota Transplant National Registry
RECRUITING
-
Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients
RECRUITING · Phase 2
-
Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile Strains
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06232551 · 152,000 participants · NA
Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism
- NCT06917339 · 156,000 participants
Retrospective Analyses of TrakStar Database
- NCT05994482 · 130,000 participants
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
- NCT02693509 · 128,026 participants
Get With The Guidelines-Heart Failure Registry
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI