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NCT04014608 · ClinicalTrials.gov registry record

Protocol for Admission Toxigenic C. Difficile Surveillance

A clinical trial of Clostridium Difficile Infection, sponsored by Endeavor Health.

Completed
Registry status
148,549
Enrollment target
1
Study location

NCT04014608 is a study of Clostridium Difficile Infection that has completed, run by Endeavor Health. The registered enrollment target is 148,549 participants, above the 639-participant average among 13 other Clostridium Difficile Infection trials with a reported enrollment target (23147% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT04014608, a study of Clostridium Difficile Infection, has completed, sponsored by Endeavor Health.

COMPLETED
Registry status
148,549 participants
Enrollment target
1
Study location

Study Summary

Background: Clostridioides (formerly Clostridium) difficile Infection (CDI) is a persistent healthcare issue. In the US, CDI is the most common infectious cause of hospital-onset (HO) diarrhea. Objective: Assess the impact of admission testing for toxigenic C. difficile colonization on the incidence of clinical disease. Design: Pragmatic stepped-wedge Infection Control initiative. Setting: NorthShore University HealthSystem (NorthShore) is a four-hospital system near Chicago, Illinois. Patients: All patients admitted to the four hospitals during the initiative. Interventions: From September 2017 through August 2018 the investigators conducted a quality improvement program where admitted patients had a peri-rectal swab tested for toxigenic C. difficile. All colonized patients were placed in contact precautions. Measurements: The investigators tested admissions who: i) had been hospitalized within two months, ii) had a past C. difficile positive test, and/or iii) were in a long-term care facility within six months. The investigators measured compliance with all other measures to reduce the incidence of HO-CDI. Limitations: This was not a randomized controlled trial, and multiple prevention interventions were in place at the time of the admission surveillance initiative.

Interventions

  • OTHER Standard Practice to Prevent Hospital Onset CDI

Study Locations (1)

Illinois

  • NorthShore University HealthSystem Research Institute - Evanston

Trial Details

FieldValue
Enrollment Target 148,549 participants
Start Date 2016-07-01
Est. Completion 2018-12-31

Sponsor

Endeavor Health

94 total trials

What the Registry Record Tells You About NCT04014608

The ClinicalTrials.gov registry entry for NCT04014608 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 148,549 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 639-participant average among 13 other Clostridium Difficile Infection trials with a reported enrollment target (23147% higher). The listed sponsor is Endeavor Health, which has 94 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Clostridium Difficile Infection appearing as the primary indexed condition, and to 1 intervention - of which Standard Practice to Prevent Hospital Onset CDI is the first listed.

NCT04014608 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT04014608 about?

NCT04014608 is a clinical study titled "Protocol for Admission Toxigenic C. Difficile Surveillance". Background: Clostridioides (formerly Clostridium) difficile Infection (CDI) is a persistent healthcare issue. In the US, CDI is the most common infectious cause of hospital-onset (HO) diarrhea. Objective: Assess the impact of admission testing for toxigenic C. difficile colonization on the incidenc...

What is the current status of trial NCT04014608?

This trial is currently completed. The enrollment target is 148,549 participants. The study started on 2016-07-01. Estimated completion is 2018-12-31.

What conditions does trial NCT04014608 study?

This clinical trial studies the following conditions: Clostridium Difficile Infection.

What interventions are being tested in trial NCT04014608?

The interventions under investigation include: Standard Practice to Prevent Hospital Onset CDI (OTHER).

Who is sponsoring clinical trial NCT04014608?

This trial is sponsored by Endeavor Health, which has 94 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04014608 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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