Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Clostridium Difficile: early-phase trial registry
2 of 7 indexed Clostridium Difficile trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 2 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Clostridium Difficile: 7 US clinical trials tracked, 2 recruiting.
Clostridium Difficile is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Romark Laboratories L.C., running 1 of these trials.
Enrollment posture brief
Registry condition clostridium-difficile
OPEN 2 | RECR 29% | LATE 1 | EARLY 4 | RANK #2497 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acromegaly (29% recruiting · 14 trials)
Clostridium Difficile lists 2 open slots (29% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Clostridium Difficile on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Clostridium Difficile is recruiting below its size-band peers.
2 of 7 indexed trials (28.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Clostridium Difficile trials is spread across many organizations.
Romark Laboratories L.C. accounts for 1 of 7 trials (14.3%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Clostridium Difficile enrolment sits around 200 participants.
Median target enrolment is 200 among the 7 trials that report a genuine target (sentinel values excluded). 2 of those (28.6%) plan for fewer than 100 participants.
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Clostridium Difficile research is mostly interventional.
5 interventional and 2 observational studies make up this index (71.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients
The Methodist Hospital Research Institute
NCT06258551
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Vedanta Biosciences
NCT06237452
REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs
University of Pennsylvania
NCT05622721
Dose-Confirmation, Immunogenicity and Safety Study of the Clostridium Difficile Vaccine Candidate VLA84 in Healthy Adults Aged 50 Years and Older. Phase II Study
Valneva Austria
NCT02316470
Study of Nitazoxanide in the Treatment of Clostridium Difficile Colitis
Romark Laboratories L.C.
NCT00417872
SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)
Seres Therapeutics
NCT02437487
Early FMT for C.Difficile
Emory University
NCT02465463
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Clostridium Difficile records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Clostridium Difficile trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Clostridium Difficile page
7 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Clostridium Difficile trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Romark Laboratories L.C. sponsors the most Clostridium Difficile trials on record, review their full trial history before evaluating a specific study. See Romark Laboratories L.C.'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Clostridium Difficile condition card totals 7 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.