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ClinicalTrials.gov 1 recruiting now official registry

Chronic Myeloid Leukemia (CML) clinical trials

1 of 8 indexed Chronic Myeloid Leukemia (CML) trials are currently recruiting.

8 US clinical trials · 1 currently recruiting

Chronic Myeloid Leukemia (CML) is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 3 of these trials.

The research picture

Chronic Myeloid Leukemia (CML) has 8 registered US clinical trials, 1 of them open to new participants right now, about 13% of the total.

1
recruiting participants now
13%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Phase 13Phase 24

Active & Recent Trials

8 total, page 1 of 1

RECRUITING Phase 1 12 participants

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Ossium Health

NCT05589896

ACTIVE NOT RECRUITING Phase 2 170 participants

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

St. Jude Children's Research Hospital

NCT02790515

ACTIVE NOT RECRUITING Phase 2 69 participants

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

St. Jude Children's Research Hospital

NCT03849651

ACTIVE NOT RECRUITING Phase 1 14 participants

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Diane George

NCT02061800

COMPLETED 186 participants

Healthcare Costs Among Patients With CML Receiving Dasatinib or Nilotinib in a Commercial and Medicare Population

Bristol-Myers Squibb

NCT02363868

COMPLETED Phase 1 35 participants

Natural Killer Cells and Bortezomib to Treat Cancer

National Heart, Lung, and Blood Institute (NHLBI)

NCT00720785

COMPLETED Phase 2 10 participants

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

National Heart, Lung, and Blood Institute (NHLBI)

NCT00488592

COMPLETED Phase 2 4 participants

Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy

National Heart, Lung, and Blood Institute (NHLBI)

NCT00433745

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Myeloid Leukemia (CML) Trial Landscape

8 indexed Chronic Myeloid Leukemia (CML) studies · 1 recruiting (13%).

Phase mix: 0 late (III/IV) vs 7 early (I/II).

Top sponsor: National Heart, Lung, and Blood Institute (NHLBI) (3 trials), 4 others listed. 8 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Myeloid Leukemia (CML)?

PlainTrial tracks 8 US clinical trials for Chronic Myeloid Leukemia (CML), of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Myeloid Leukemia (CML)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.