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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: early-phase trial registry

5 of 8 indexed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 5 currently recruiting · #2,176 of 28,707 conditions by registered trial count

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: 8 US clinical trials tracked, 5 recruiting.

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is City of Hope Medical Center, running 2 of these trials.

Enrollment posture brief

Registry condition chronic-lymphocytic-leukemiasmall-lymphocytic-lymphoma

OPEN 5 | RECR 63% | LATE 0 | EARLY 6 | RANK #2176 | SPON 2

Nearest open-share peer: Adolescent (63% recruiting · 16 trials)

Activity, Motor75%Chronic Lymphocytic Leuk (th…63%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%
Open-enrollment share among volume-matched conditions near Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma lists 5 open slots (63% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma is recruiting above its size-band peers.

    5 of 8 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma research.

    City of Hope Medical Center accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 8 trials that report a genuine target (sentinel values excluded). 8 of those (100%) plan for fewer than 100 participants.

  4. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma research is mostly interventional.

    8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 24

Open and recent trials

8 total, page 1 of 1

RECRUITING NA 70 participants

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

Mayo Clinic

NCT05876923

RECRUITING Phase 2 61 participants

Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Seema Bhat

NCT06757647

RECRUITING NA 50 participants

Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors

Northwell Health

NCT05643235

RECRUITING Phase 1 37 participants

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT06859008

RECRUITING Phase 2 34 participants

LP-168 and Obinutuzumab for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This

Zulfa Omer

NCT06978088

ACTIVE NOT RECRUITING Phase 2 60 participants

Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

M.D. Anderson Cancer Center

NCT04458610

ACTIVE NOT RECRUITING Phase 2 4 participants

Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia

City of Hope Medical Center

NCT04657094

COMPLETED Phase 1 45 participants

A Phase I/Ib Safety and Efficacy Study of the PI3K-delta Inhibitor TGR-1202 and Ibrutinib in Patients With CLL or MCL

Dana-Farber Cancer Institute

NCT02268851

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4

Named interventions

Most-linked intervention names on Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
3 trials
Acalabrutinib Drug
2 trials
Computed Tomography Procedure
2 trials
Bone Marrow Biopsy Procedure
2 trials
Bone Marrow Aspiration Procedure
2 trials
TGR-1202 Drug
1 trials
Dual X-ray Absorptiometry Procedure
1 trials
Cardiopulmonary Exercise Testing Other
1 trials

US sites by state

Facility locations filed on Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma trials. A trial with sites in several states counts in each.

California 3 trials
Ohio 2 trials
Texas 1 trials
New York 1 trials
Minnesota 1 trials
Maine 1 trials
Massachusetts 1 trials
Connecticut 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma page

8 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • City of Hope Medical Center sponsors the most Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma trials on record, review their full trial history before evaluating a specific study. See City of Hope Medical Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma condition card totals 8 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.