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ClinicalTrials.gov 3 recruiting now later-stage tilt small index

Chronic Insomnia: later-stage trial registry

3 of 12 indexed Chronic Insomnia trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 3 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Chronic Insomnia: 12 US clinical trials tracked, 3 recruiting.

Chronic Insomnia is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 2 of these trials.

Enrollment posture brief

Registry condition chronic-insomnia

OPEN 3 | RECR 25% | LATE 2 | EARLY 1 | RANK #1429 | SPON 2

Nearest open-share peer: Abdominal Cancer (25% recruiting · 8 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Chronic Insomnia (this)25%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Chronic Insomnia

Chronic Insomnia lists 3 open slots (25% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Insomnia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Insomnia is recruiting below its size-band peers.

    3 of 12 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Chronic Insomnia research.

    Takeda accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Insomnia enrolment sits around 135 participants.

    Median target enrolment is 135 among the 12 trials that report a genuine target (sentinel values excluded). 4 of those (33.3%) plan for fewer than 100 participants.

  4. Chronic Insomnia research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 31Phase 41

Open and recent trials

12 total, page 1 of 1

RECRUITING NA 188 participants

Comparing Insomnia Care As Usual to Digital Augmentation (CICADA)

Noctem

NCT05490550

RECRUITING NA 165 participants

Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

University of South Florida

NCT06345872

RECRUITING NA 20 participants

Insomnia Behavioral Intervention Study

University of Pennsylvania

NCT05301543

ACTIVE NOT RECRUITING NA 64 participants

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

Abramson Cancer Center at Penn Medicine

NCT05226078

COMPLETED 277,920 participants

Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics

VA Office of Research and Development

NCT04350866

COMPLETED Phase 3 405 participants

Study of Efficacy of Ramelteon in Adults With Chronic Insomnia

Takeda

NCT00671125

COMPLETED NA 195 participants

Insomnia Self-Management in Heart Failure

Yale University

NCT02660385

COMPLETED Phase 4 135 participants

Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia

Takeda

NCT00492232

COMPLETED NA 132 participants

Brief Behavioral Treatment for Insomnia in Cancer Survivors

State University of New York at Buffalo

NCT03810365

COMPLETED NA 112 participants

Naturalistic Monitoring and Treatment of Chronic Insomnia

Washington State University

NCT04013321

COMPLETED Phase 2 30 participants

Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study

University of Minnesota

NCT00515177

COMPLETED NA 20 participants

Sleep and Pain Intervention for Chronic Widespread Pain Pilot Study

University of Missouri-Columbia

NCT02688569

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Chronic Insomnia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cognitive Behavioral Therapy for Insomnia Behavioral
2 trials
Self-Management Education for Heart Failure Behavioral
1 trials
Expert Recommendations for Implementing Change bundle of strategies Behavioral
1 trials
Healthy Eating Control Behavioral
1 trials
Brief behavioral treatment for insomnia Behavioral
1 trials
Online CBTi Behavioral
1 trials
SleepScore Max coaching feature Device
1 trials
Placebo and zolpidem Drug
1 trials

US sites by state

Facility locations filed on Chronic Insomnia trials. A trial with sites in several states counts in each.

Pennsylvania 3 trials
Florida 3 trials
Washington 2 trials
New York 2 trials
Kentucky 2 trials
Georgia 2 trials
California 2 trials
Arkansas 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Insomnia page

12 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 3 Chronic Insomnia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Takeda sponsors the most Chronic Insomnia trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Insomnia condition card totals 12 registered trials; most-linked intervention Cognitive Behavioral Therapy for Insomnia; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.