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2026 data Public-data reference. official source

Carpal Tunnel Syndrome

Open-data reference.

22 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING 360 participants

Ultrasound Analysis of Human Carpal Tunnel System

Mayo Clinic

NCT02747836

RECRUITING 300 participants

Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Henry Ford Health System

NCT04737239

RECRUITING NA 128 participants

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

University of Chicago

NCT05783245

RECRUITING NA 116 participants

Carpal Arch Space Augmentation (CASA) Clinical Trial

University of Arizona

NCT06208709

RECRUITING NA 95 participants

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Spaulding Rehabilitation Hospital

NCT04206215

RECRUITING Phase 4 64 participants

Exparel and Education to Avoid Opioids After Carpal Tunnel Release

Kettering Health Network

NCT03867539

RECRUITING NA 48 participants

Small Nerve Fiber Activity in Patients with Carpal Tunnel Syndrome Assessed Via Quantitative Sensory Testing

Brooke Army Medical Center

NCT06550284

RECRUITING NA 30 participants

Efficacy of Red Kinesiology Tape on Carpal Tunnel-Like Symptoms and Performance in Esports Gamers

University of Nevada, Las Vegas

NCT06757062

ACTIVE NOT RECRUITING 2,000 participants

Registry of the Patient Experience for Carpal Tunnel Release

Sonex Health

NCT06071468

ACTIVE NOT RECRUITING NA 84 participants

Postoperative Care After Carpal Tunnel Release Using Short Educational Videos

Carilion Clinic

NCT06647719

COMPLETED 333 participants

Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies

University of South Florida

NCT02788734

COMPLETED Phase 4 184 participants

Preoperative Antibiotics for Carpal Tunnel Release Surgery

WellSpan Health

NCT03432858

COMPLETED NA 184 participants

Cost Information on Carpal Tunnel Syndrome Treatment Decisions

University of Texas at Austin

NCT03880812

COMPLETED 150 participants

Work and Health Disparities Among Rural Women

National Institute of Environmental Health Sciences (NIEHS)

NCT00042419

COMPLETED NA 124 participants

Prospective Randomized Trial of Monocryl Versus Nylon Suture Closure in Carpal Tunnel Surgery

University of California, Davis

NCT03950401

COMPLETED NA 122 participants

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

Sonex Health

NCT05405218

COMPLETED NA 100 participants

Post-operative Mobilization for Carpal Tunnel Syndrome

Vanderbilt University

NCT00435149

COMPLETED Phase 4 62 participants

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Endo Pharmaceuticals

NCT00904202

COMPLETED NA 60 participants

Local Effects of Acupuncture and Nerve Conduction Studies

Oregon Health and Science University

NCT03036657

COMPLETED Phase 1 52 participants

The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

University of South Florida

NCT03729375

COMPLETED Phase 1 40 participants

Mechanisms of Neural Mobilization in the Treatment of Chronic Pain

University of Florida

NCT00929123

COMPLETED NA 40 participants

Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery

University of Texas at Austin

NCT06188221

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Carpal Tunnel Syndrome Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Carpal Tunnel Syndrome, and 8 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Carpal Tunnel Syndrome shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Carpal Tunnel Syndrome is led by Sonex Health with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Carpal Tunnel Syndrome?

PlainTrial tracks 22 US clinical trials for Carpal Tunnel Syndrome, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Carpal Tunnel Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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