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ClinicalTrials.gov 1 recruiting now later-stage tilt small index

Anterior Cruciate Ligament Tear: later-stage trial registry

1 of 12 indexed Anterior Cruciate Ligament Tear trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 1 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Anterior Cruciate Ligament Tear: 12 US clinical trials tracked, 1 recruiting.

Anterior Cruciate Ligament Tear is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Miach Orthopaedics, running 2 of these trials.

Enrollment posture brief

Registry condition anterior-cruciate-ligament-tear

OPEN 1 | RECR 8% | LATE 2 | EARLY 1 | RANK #1429 | SPON 2

Nearest open-share peer: Allergic Rhinitis (8% recruiting · 24 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Anterior Cruciate Ligame (th…8%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Anterior Cruciate Ligament Tear

Anterior Cruciate Ligament Tear lists 1 open slots (8% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anterior Cruciate Ligament Tear on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anterior Cruciate Ligament Tear is recruiting below its size-band peers.

    1 of 12 indexed trials (8.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Anterior Cruciate Ligament Tear research.

    Miach Orthopaedics accounts for 2 of 12 trials (16.7%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anterior Cruciate Ligament Tear enrolment sits around 100 participants.

    Median target enrolment is 100 among the 12 trials that report a genuine target (sentinel values excluded). 6 of those (50%) plan for fewer than 100 participants.

  4. Anterior Cruciate Ligament Tear research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 42

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 4 84 participants

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

The Methodist Hospital Research Institute

NCT06511232

ACTIVE NOT RECRUITING NA 150 participants

Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial

University of Colorado, Denver

NCT04039971

ACTIVE NOT RECRUITING NA 150 participants

A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction

The Cleveland Clinic

NCT03776162

ACTIVE NOT RECRUITING NA 100 participants

Bridge-Enhanced ACL Repair vs ACL Reconstruction

Miach Orthopaedics

NCT02664545

ACTIVE NOT RECRUITING NA 100 participants

Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair

Henry Ford Health System

NCT05494073

ACTIVE NOT RECRUITING NA 28 participants

Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery

Sanford Health

NCT06524349

ACTIVE NOT RECRUITING NA 20 participants

Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

Miach Orthopaedics

NCT02292004

COMPLETED 1,646 participants

Prospective Registry of Anterior Cruciate Ligament Reconstructions

State University of New York at Buffalo

NCT04135950

COMPLETED Phase 4 132 participants

Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength

University of California, San Francisco

NCT05190120

COMPLETED NA 50 participants

Regenexx™ SD Versus Exercise Therapy for ACL Tears

Regenexx

NCT01850758

COMPLETED NA 50 participants

Use of Blood Flow Restriction Therapy Following ACL Tear

Henry Ford Health System

NCT04374968

COMPLETED Phase 2 24 participants

Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

Andrews Research & Education Foundation

NCT04088227

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 2

Named interventions

Most-linked intervention names on Anterior Cruciate Ligament Tear records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Blood flood restriction cuff Device
1 trials
Experimental Group Drug
1 trials
Exercise Therapy Other
1 trials
Regenexx SD Procedure
1 trials
Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml. Drug
1 trials
preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine Drug
1 trials
Adductor Canal Nerve Block Procedure
1 trials
Femoral Nerve Block Procedure
1 trials

US sites by state

Facility locations filed on Anterior Cruciate Ligament Tear trials. A trial with sites in several states counts in each.

Colorado 3 trials
Michigan 2 trials
Massachusetts 2 trials
Texas 1 trials
Tennessee 1 trials
South Dakota 1 trials
Rhode Island 1 trials
Ohio 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anterior Cruciate Ligament Tear page

12 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 1 Anterior Cruciate Ligament Tear trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Miach Orthopaedics sponsors the most Anterior Cruciate Ligament Tear trials on record, review their full trial history before evaluating a specific study. See Miach Orthopaedics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anterior Cruciate Ligament Tear condition card totals 12 registered trials; most-linked intervention Blood flood restriction cuff; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.