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ClinicalTrials.gov 1 recruiting now official registry

Anterior Cruciate Ligament Tear clinical trials

1 of 12 indexed Anterior Cruciate Ligament Tear trials are currently recruiting.

12 US clinical trials · 1 currently recruiting

Anterior Cruciate Ligament Tear is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Miach Orthopaedics, running 2 of these trials.

The research picture

Anterior Cruciate Ligament Tear has 12 registered US clinical trials, 1 of them open to new participants right now, about 8% of the total.

1
recruiting participants now
8%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Miach Orthopaedics
Phase 21Phase 42

Active & Recent Trials

12 total, page 1 of 1

RECRUITING Phase 4 84 participants

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

The Methodist Hospital Research Institute

NCT06511232

ACTIVE NOT RECRUITING NA 150 participants

Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial

University of Colorado, Denver

NCT04039971

ACTIVE NOT RECRUITING NA 150 participants

A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction

The Cleveland Clinic

NCT03776162

ACTIVE NOT RECRUITING NA 100 participants

Bridge-Enhanced ACL Repair vs ACL Reconstruction

Miach Orthopaedics

NCT02664545

ACTIVE NOT RECRUITING NA 100 participants

Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair

Henry Ford Health System

NCT05494073

ACTIVE NOT RECRUITING NA 28 participants

Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery

Sanford Health

NCT06524349

ACTIVE NOT RECRUITING NA 20 participants

Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

Miach Orthopaedics

NCT02292004

COMPLETED 1,646 participants

Prospective Registry of Anterior Cruciate Ligament Reconstructions

State University of New York at Buffalo

NCT04135950

COMPLETED Phase 4 132 participants

Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength

University of California, San Francisco

NCT05190120

COMPLETED NA 50 participants

Regenexx™ SD Versus Exercise Therapy for ACL Tears

Regenexx

NCT01850758

COMPLETED NA 50 participants

Use of Blood Flow Restriction Therapy Following ACL Tear

Henry Ford Health System

NCT04374968

COMPLETED Phase 2 24 participants

Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

Andrews Research & Education Foundation

NCT04088227

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anterior Cruciate Ligament Tear Trial Landscape

12 indexed Anterior Cruciate Ligament Tear studies · 1 recruiting (8%).

Phase mix: 2 late (III/IV) vs 1 early (I/II).

Top sponsor: Miach Orthopaedics (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anterior Cruciate Ligament Tear?

PlainTrial tracks 12 US clinical trials for Anterior Cruciate Ligament Tear, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anterior Cruciate Ligament Tear?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.