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NCT05964387 · ClinicalTrials.gov registry record · NA
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
A NA study of Anesthesia, Local and Molar Incisor Hypomineralization, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05964387: Recruiting NA study of Anesthesia, Local and Molar Incisor Hypomineralization, sponsored by University of Michigan.
NCT05964387 is a NA study of Anesthesia, Local and Molar Incisor Hypomineralization that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 50 participants, below the 80-participant average among 18 other Anesthesia, Local trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05964387, a NA study of Anesthesia, Local and Molar Incisor Hypomineralization, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia (MIH). The goal is to determine if pre-operative application of SDF results in improved local anesthesia and decrease in procedural pain in MIH affected teeth, thereby addressing an important challenge in routine clinical practice and contributing to the development of a treatment protocol for MIH affected molars.
Primary Outcome
Four point scale evaluating efficacy of local anesthesia
Conditions Studied
Interventions
- DEVICE SDF
- DEVICE Placebo
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-06-12 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What NCT05964387 shows while recruiting
NCT05964387 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 80-participant average among 18 other Anesthesia, Local trials with a reported enrollment target (37% lower).
The record links to 2 conditions, with Anesthesia, Local appearing as the primary indexed condition, and to 2 interventions - of which SDF is the first listed.
NCT05964387 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT05964387 about?
NCT05964387 is a clinical study titled "Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars". The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia (MIH). The goal is to determine if pre-operative application of SDF result...
What is the current status of trial NCT05964387?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-06-12. Estimated completion is 2027-12-31.
What conditions does trial NCT05964387 study?
This clinical trial studies the following conditions: Anesthesia, Local, Molar Incisor Hypomineralization.
What interventions are being tested in trial NCT05964387?
The interventions under investigation include: SDF (DEVICE), Placebo (DEVICE).
Who is sponsoring clinical trial NCT05964387?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05964387 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anesthesia, Local
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05964387's enrollment target sits among peer trials
50 11th of 18 higher than 8 of 18 other Anesthesia, Local trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia, Local trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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