Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov enrollment closed early-phase tilt small index

Adult Anaplastic Astrocytoma: early-phase trial registry

A small indexed set (8 trials) with no open enrollment listed right now.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · none currently recruiting · #2,176 of 28,707 conditions by registered trial count

Adult Anaplastic Astrocytoma: 8 US clinical trials tracked, none currently recruiting.

Adult Anaplastic Astrocytoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

Enrollment posture brief

Registry condition adult-anaplastic-astrocytoma

OPEN 0 | RECR 0% | LATE 0 | EARLY 8 | RANK #2176 | SPON 4

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

Activity, Motor75%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%Adult Anaplastic Astrocy (th…0%
Open-enrollment share among volume-matched conditions near Adult Anaplastic Astrocytoma

Adult Anaplastic Astrocytoma has no open enrollment in this registry pull (8 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Adult Anaplastic Astrocytoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Adult Anaplastic Astrocytoma is recruiting below its size-band peers.

    0 of 8 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Adult Anaplastic Astrocytoma research.

    National Cancer Institute (NCI) accounts for 4 of 8 trials (50%). 3 distinct sponsors appear on at least one study for this condition label.

  3. Most Adult Anaplastic Astrocytoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 22 among the 8 trials that report a genuine target (sentinel values excluded). 7 of those (87.5%) plan for fewer than 100 participants.

  4. Adult Anaplastic Astrocytoma research is mostly interventional.

    8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18

Indexed trials (enrollment closed)

8 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 1 83 participants

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

National Cancer Institute (NCI)

NCT00268385

COMPLETED Phase 1 136 participants

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

National Cancer Institute (NCI)

NCT00045110

COMPLETED Phase 1 69 participants

Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma

National Cancer Institute (NCI)

NCT00112736

COMPLETED Phase 1 22 participants

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

National Cancer Institute (NCI)

NCT01119599

COMPLETED Phase 1 17 participants

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT02186509

COMPLETED Phase 1 16 participants

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

City of Hope Medical Center

NCT02015819

COMPLETED Phase 1 15 participants

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

City of Hope Medical Center

NCT01172964

COMPLETED Phase 1 7 participants

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

City of Hope Medical Center

NCT01234740

Phase Distribution

PhaseTrial count
Phase 1 8

Named interventions

Most-linked intervention names on Adult Anaplastic Astrocytoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

pharmacological study Other
5 trials
laboratory biomarker analysis Other
3 trials
flucytosine Drug
2 trials
Pharmacological Study Other
2 trials
Laboratory Biomarker Analysis Other
2 trials
gene therapy Biological
1 trials
polymerase chain reaction Other
1 trials
Hyperfractionated radiation therapy Radiation
1 trials

US sites by state

Facility locations filed on Adult Anaplastic Astrocytoma trials. A trial with sites in several states counts in each.

California 6 trials
Pennsylvania 4 trials
Wisconsin 3 trials
Texas 3 trials
New York 3 trials
Maryland 3 trials
Massachusetts 2 trials
Virginia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Adult Anaplastic Astrocytoma page

8 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Adult Anaplastic Astrocytoma trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • National Cancer Institute (NCI) sponsors the most Adult Anaplastic Astrocytoma trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Adult Anaplastic Astrocytoma condition card totals 8 registered trials; most-linked intervention pharmacological study; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.