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NCT06026371 · ClinicalTrials.gov registry record · Phase 2
Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation
A Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Acute-graft-versus-host Disease, sponsored by Fred Hutchinson Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 138
- Enrollment target
- 1
- Study location
NCT06026371 is a Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Acute-graft-versus-host Disease that is active but no longer recruiting, run by Fred Hutchinson Cancer Center. The registered enrollment target is 138 participants, below the 481-participant average among 62 other Hematopoietic and Lymphatic System Neoplasm trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06026371, a Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Acute-graft-versus-host Disease, is active but no longer recruiting, sponsored by Fred Hutchinson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 138 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized placebo-controlled double-blind phase II trial tests whether fecal microorganism (microbiota) transplantation prevents severe acute graft versus host disease in adults undergoing allogeneic hematopoietic cell transplantation (HCT). Fecal microbiota transplantation involves receiving processed fecal material orally after allogeneic HCT in order to establish a healthy gut microbiota. Gut microbiota undergoes major alterations during allogeneic HCT because of antibiotic exposures, nutritional changes, and chemotherapy administration. Establishing a healthy gut microbiota via fecal transplantation may help prevent acute graft versus host disease in patients undergoing allogeneic HCT.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Fecal Microbiota Transplantation Capsule
Study Locations (1)
Washington
- Fred Hutch/University of Washington Cancer Consortium - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2023-12-12 |
| Est. Completion | 2027-03-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06026371
The ClinicalTrials.gov registry entry for NCT06026371 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 138 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 481-participant average among 62 other Hematopoietic and Lymphatic System Neoplasm trials with a reported enrollment target (71% lower). The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hematopoietic and Lymphatic System Neoplasm appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06026371 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.
Frequently Asked Questions
What is clinical trial NCT06026371 about?
NCT06026371 is a clinical study titled "Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation". This randomized placebo-controlled double-blind phase II trial tests whether fecal microorganism (microbiota) transplantation prevents severe acute graft versus host disease in adults undergoing allogeneic hematopoietic cell transplantation (HCT). Fecal microbiota transplantation involves receiving ...
What is the current status of trial NCT06026371?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 138 participants. The study started on 2023-12-12. Estimated completion is 2027-03-31.
What conditions does trial NCT06026371 study?
This clinical trial studies the following conditions: Hematopoietic and Lymphatic System Neoplasm, Acute-graft-versus-host Disease.
What interventions are being tested in trial NCT06026371?
The interventions under investigation include: Placebo (DRUG), Fecal Microbiota Transplantation Capsule (DRUG).
Who is sponsoring clinical trial NCT06026371?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06026371 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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