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NCT07419685 · ClinicalTrials.gov registry record · NA
Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste
A NA study of Dental Caries, sponsored by Church & Dwight Company.
- Completed
- Registry status
- NA
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT07419685: Completed NA study of Dental Caries, sponsored by Church & Dwight Company.
NCT07419685 is a NA study of Dental Caries that has completed, run by Church & Dwight Company. The registered enrollment target is 31 participants, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07419685, a NA study of Dental Caries, has completed, sponsored by Church & Dwight Company.
- COMPLETED
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices-one fluoride-free negative control, one positive control with 0.243% sodium fluoride, and one investigational dentifrice containing 0.243% sodium fluoride and 20% sodium bicarbonate. Healthy adult subjects wore a palatal acrylic appliance containing demineralized enamel specimens for three 9-day treatment periods, during which in vivo brushing/slurry exposure and ex vivo sucrose challenges were performed. Outcomes included percent surface microhardness recovery (%SMHR) and post-treatment enamel fluoride concentration.
Conditions Studied
Interventions
- DRUG Active Comparator
- DRUG Negative Control Toothpaste
- DRUG Test Toothpaste
Study Locations (1)
Indiana
- Therametric Technologies, Inc. - Noblesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2024-10-08 |
| Est. Completion | 2025-01-17 |
| Phase | NA |
What the finished NCT07419685 record still lists
NCT07419685 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Dental Caries appearing as the primary indexed condition, and to 3 interventions - of which Active Comparator is the first listed.
NCT07419685 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07419685 about?
NCT07419685 is a clinical study titled "Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste". This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices-one fluoride-free negative control, one positive control with 0.243% sodium fluoride, and one investigational dentifric...
What is the current status of trial NCT07419685?
This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2024-10-08. Estimated completion is 2025-01-17.
What conditions does trial NCT07419685 study?
This clinical trial studies the following conditions: Dental Caries.
What interventions are being tested in trial NCT07419685?
The interventions under investigation include: Active Comparator (DRUG), Negative Control Toothpaste (DRUG), Test Toothpaste (DRUG).
Who is sponsoring clinical trial NCT07419685?
This trial is sponsored by Church & Dwight Company, which has 19 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07419685 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dental Caries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07419685's enrollment target sits among peer trials
31 24th of 30 higher than 7 of 30 other Dental Caries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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