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NCT07284641 · ClinicalTrials.gov registry record · Phase 2
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
A Phase 2 study of DiGeorge Syndrome and Immune Dysregulation, sponsored by Paul Szabolcs.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT07284641 is a Phase 2 study of DiGeorge Syndrome and Immune Dysregulation that is actively recruiting participants, run by Paul Szabolcs. The registered enrollment target is 25 participants, below the 447-participant average among 4 other DiGeorge Syndrome trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07284641, a Phase 2 study of DiGeorge Syndrome and Immune Dysregulation, is actively recruiting participants, sponsored by Paul Szabolcs.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a research protocol that will examine Hematopoietic Stem Cell Transplantation (HSCT) using a reduced conditioning regimen (RIC) with total body Irradiation (TBI) in those diagnosed with Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD).
Conditions Studied
Interventions
- BIOLOGICAL Hematopoietic stem cell transplant (HSCT)
Study Locations (1)
Pennsylvania
- UPMC Children's Hospital of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2026-03-01 |
| Est. Completion | 2031-02-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07284641
The ClinicalTrials.gov registry entry for NCT07284641 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 447-participant average among 4 other DiGeorge Syndrome trials with a reported enrollment target (94% lower). The listed sponsor is Paul Szabolcs, which has 7 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with DiGeorge Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Hematopoietic stem cell transplant (HSCT) is the first listed.
NCT07284641 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07284641 about?
NCT07284641 is a clinical study titled "Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)". This is a research protocol that will examine Hematopoietic Stem Cell Transplantation (HSCT) using a reduced conditioning regimen (RIC) with total body Irradiation (TBI) in those diagnosed with Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory D...
What is the current status of trial NCT07284641?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2026-03-01. Estimated completion is 2031-02-01.
What conditions does trial NCT07284641 study?
This clinical trial studies the following conditions: DiGeorge Syndrome, Immune Dysregulation, Primary Immune Regulatory Disorder, Common Variable Immunodeficiency (CVID), CD40 Ligand Deficiency.
What interventions are being tested in trial NCT07284641?
The interventions under investigation include: Hematopoietic stem cell transplant (HSCT) (BIOLOGICAL).
Who is sponsoring clinical trial NCT07284641?
This trial is sponsored by Paul Szabolcs, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07284641 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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