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COMPLETED Phase 2

Thymus Transplantation Dose in DiGeorge #932

NCT00576836 · View on ClinicalTrials.gov ↗

Study Summary

One purpose of this study is to determine whether the amount of cultured thymus tissue implanted into DiGeorge anomaly infants has any effect on the immune outcome. Another purpose of this study is to determine whether parental parathyroid transplantation (in addition to cultured thymus tissue implantation (CTTI) can help both the immune and the calcium problems in DiGeorge infants with hypocalcemia. \[Funding Source - FDA Office of Orphan Products Development (OOPD)\]

Interventions

  • BIOLOGICAL Cultured Thymus Tissue Implantation (CTTI)
  • OTHER Cultured Thymus Tissue Implantation with Parathyroid Transplantation

Study Locations (1)

North Carolina

  • Duke University Medical Center — Durham

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2004-09-02
Est. Completion 2019-12-31
Phase Phase 2

Sponsor

Sumitomo Pharma Switzerland

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00576836

The ClinicalTrials.gov registry entry for NCT00576836 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sumitomo Pharma Switzerland, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with DiGeorge Syndrome appearing as the primary indexed condition, and to 2 interventions — of which Cultured Thymus Tissue Implantation (CTTI) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00576836 reports 1 study location spanning 1 distinct geographic area — top geographies include North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00576836 about?

NCT00576836 is a clinical study titled "Thymus Transplantation Dose in DiGeorge #932". One purpose of this study is to determine whether the amount of cultured thymus tissue implanted into DiGeorge anomaly infants has any effect on the immune outcome. Another purpose of this study is to determine whether parental parathyroid transplantation (in addition to cultured thymus tissue impla...

What is the current status of trial NCT00576836?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2004-09-02. Estimated completion is 2019-12-31.

What conditions does trial NCT00576836 study?

This clinical trial studies the following conditions: DiGeorge Syndrome, Complete DiGeorge Anomaly, Complete DiGeorge Syndrome, DiGeorge Anomaly. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00576836?

The interventions under investigation include: Cultured Thymus Tissue Implantation (CTTI) (BIOLOGICAL), Cultured Thymus Tissue Implantation with Parathyroid Transplantation (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00576836?

This trial is sponsored by Sumitomo Pharma Switzerland, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00576836 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial