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NCT06939348 · ClinicalTrials.gov registry record · NA
Ultrasound Stimulation for Patients in a Disorder of Consciousness
A NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 4
- Study locations
NCT06939348 is a NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 60 participants, above the 48-participant average among 4 other Consciousness Disorders trials with a reported enrollment target (25% higher). The trial reports 4 study locations across 2 states.
The verdict
NCT06939348, a NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 4
- Study locations
Study Summary
The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this multicenter project aims to (1) establish short-term efficacy of tFUS as a therapeutic to promote recovery in patients with prolonged DoC as compared to sham treatment, (2) establish dose-related safety and efficacy of tFUS as a therapeutic intervention in prolonged DoC patients and (3) explore preliminary predictors and biomarkers of susceptibility and response to thalamic sonication.
Conditions Studied
Interventions
- DEVICE The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain.
Study Locations (4)
California
- The Regents of the University of California, Los Angeles - Los Angeles
- Casa Colina Hospital and Centers for Healthcare - Pomona
Massachusetts
- Massachusetts General Hospital (The General Hospital Corp.) - Boston
- Spaulding Rehabilitation Hospital Corporation, Inc. - Charlestown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-04-26 |
| Est. Completion | 2028-09-29 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06939348
The ClinicalTrials.gov registry entry for NCT06939348 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 48-participant average among 4 other Consciousness Disorders trials with a reported enrollment target (25% higher). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Consciousness Disorders appearing as the primary indexed condition, and to 1 intervention - of which The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain. is the first listed.
NCT06939348 reports 4 study locations spanning 2 distinct geographic areas - top geographies include California, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06939348 about?
NCT06939348 is a clinical study titled "Ultrasound Stimulation for Patients in a Disorder of Consciousness". The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this multicenter project aims to (1) establish short-term efficacy of tFUS as a therapeutic to promote recovery in patients with p...
What is the current status of trial NCT06939348?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-04-26. Estimated completion is 2028-09-29.
What conditions does trial NCT06939348 study?
This clinical trial studies the following conditions: Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury.
What interventions are being tested in trial NCT06939348?
The interventions under investigation include: The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain. (DEVICE).
Who is sponsoring clinical trial NCT06939348?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06939348 being conducted?
This trial has 4 study locations across California, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Disorders of Consciousness Due to Severe Brain Injury
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