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RECRUITING NA

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.1

NCT07215299 · View on ClinicalTrials.gov ↗

Study Summary

In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal role of deep brain structures in cognition. In the short term, the investigators aim to validate and characterize the effects of TI on brain activity as measured by fMRI and demonstrate its ability to focally stimulate deep brain regions without affecting overlying cortex. In the longer term, investigators aim to use these data to resolve longstanding debates about the function of deeper brain regions and lay the foundation for future clinical applications of TI for treating addiction, Obsessive-Compulsive Disorder (OCD), Parkinson's disease, and other disorders involving deep brain dysfunction. The grant supports 2 distinct aims, each of which will be evaluated through a series of independent studies.

Conditions Studied

Interventions

  • DEVICE Temporal Interference (TI) Electrical Stimulation - NAcc TI Active
  • DEVICE Temporal Interference (TI) Electrical Stimulation - NAcc TI Sham
  • DEVICE Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Active
  • DEVICE Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Sham

Study Locations (1)

Indiana

  • Indiana University Bloomington, Imaging Research Facility — Bloomington

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-11-12
Est. Completion 2027-02-02
Phase NA

Sponsor

Indiana University

1,026 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07215299

The ClinicalTrials.gov registry entry for NCT07215299 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 1,026 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 4 interventions — of which Temporal Interference (TI) Electrical Stimulation - NAcc TI Active is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07215299 reports 1 study location spanning 1 distinct geographic area — top geographies include Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07215299 about?

NCT07215299 is a clinical study titled "Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.1". In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal role of deep brain structures in cognition. In the short term, the investigators aim to validate and characterize the effects of TI on brain...

What is the current status of trial NCT07215299?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-11-12. Estimated completion is 2027-02-02.

What conditions does trial NCT07215299 study?

This clinical trial studies the following conditions: Healthy Volunteers. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07215299?

The interventions under investigation include: Temporal Interference (TI) Electrical Stimulation - NAcc TI Active (DEVICE), Temporal Interference (TI) Electrical Stimulation - NAcc TI Sham (DEVICE), Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Active (DEVICE), Temporal Interference (TI) Electrical Stimulation - NAcc No-TI Sham (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07215299?

This trial is sponsored by Indiana University, which has 1,026 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07215299 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial